Cognitive dysfunction syndromes in dogs and cats.

Cognitive dysfunction syndromes in dogs and cats are degenerative brain diseases that are often missed until the signs become so advanced that it may be too late to help the pet or owner. in a study,researchers found that the overall prevalence of cognitive dysfunction was a little more than 14 percent, but only about 1.9 percent of cases are diagnosed. The same study found that the chances of having cognitive dysfunction increase with age, so that by the time dogs are 15 years old, 41 percent will have at least one sign consistent with cognitive decline. Neilson and Hart estimated the prevalence in geriatric dogs at 68 percent. In a 2011 review, Gunn-Moore estimated that one-third of cats 11 to 14 years old has age-related cognitive decline, which increased to more than 50 percent of cats 15 years old or older. Unfortunately, less is known about the cognitive effects of aging on senior cats than on senior dogs, but their management is similar. Cognitive dysfunction is a decline in learning, memory or awareness due to the age-related changes within the brain, and they are represented clinically by a group of signs related to varying states of dementia,although appearance is physical the root is psychological. The brains of dogs and cats undergo neuropathology as they age ,such as oxidative damage, neuronal loss, atrophy and the development of ß-amyloid plaques. These are similar changes in human brains with Alzheimer’s disease alongside other pathology that is not seen in canine (or feline) brains, they also develop these ß-amyloid plaques. The brains undergo similar pathology as they develop dementia, dogs are a great research model for human dementia. The knowledge gained from this research not only helps people, but can also help veterinarians help these pets.continue