Wednesday, March 16, 2016

PORCINE EPIDEMIC DIARRHOEA.

Porcine Epidemic Diarrhoea virus (PEDv) is devastating in herds especially in Asia and North America although the recent outbreaks of PEDv-like strains in Europe appear less destructive. Porcine Epidemic Diarrhoea (PED) is an economically important enteric disease in pigs caused by a Corona virus. Corona viruses can be divided into the genera Alpha corona virus, Beta corona virus, Gammacoronavirus and Deltacoronavirus. The Alpha corona viruses including Transmissible Gastroenteritis virus (TGEv), Porcine Respiratory Coronavirus (PRCv) and Porcine Epidemic Diarrhoea virus (PEDv) are the most important in swine. While TGEv and PRCv belong to the Alpha corona virus 1 species, PEDv belongs to a separate species within the same genus. The Beta corona viruses induce severe diseases in humans like Severe Acute Respiratory Syndrome (SARS-Cov) or Middle East Respiratory Syndrome (MERS-Cov), the Beta corona virus affecting pigs called Hemagglutinating Encephalomyelitis virus (HEv) is of minor importance for the swine industry. The Delta corona virus infections (porcine Delta corona virus, PDCov) were reported in pigs in Asia and North America which caused enteric diseases similar to PEDv but of lower clinical impact and disease severity. PED first appeared as acute diarrhoea in finishing pigs in the early 1970s in the UK and subsequently spread fast across Europe causing acute outbreaks of diarrhoea in pigs of all age groups. The routes of PEDv transmission between different areas, countries and even continents remain poorly understood. The origin of recently identified PEDv strains in Europe showing high nucleotide similarity to US S-INDEL PEDv strains remains unclear. It is not known if those strains have been circulating in the European pig population for a long time or if they were recently introduced into Europe. The various methods to applied so far to control PED virus on farms, include the following 1) Increasing sow immunity can be achieved by giving feedback. This usually involves feeding intestines or diarrheic faces from acutely infected piglets to sows to convey immunity. Different protocols are followed; no additives should be added. 2) Weaning down is also a much applied strategy – this means weaning at about ten days of age. 3)Improving biosecurity. 4)Applying strict disinfection, e.g. using Synergize, Virkon S. 5)Vaccinating. There are two inactivated vaccines available. The best success is usually achieved in pre-infected herds.

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