Wednesday, October 4, 2017

Significant epilepsy gene discovery in dogs.

Significant epilepsy gene discovery in dogs.Researh groups from the University of Helsinki, the LMU Munich and the University of Guelph have described in collaboration a novel myoclonic epilepsy in dogs and identified its genetic cause. The study reveals a novel candidate gene for human myoclonic epilepsies, one of the most common forms of epilepsy. As a result, a genetic test was developed for veterinary diagnostics and breeding programs. A collaborative study describes a novel myoclonic epilepsy syndrome in dogs for the first time and discovers its genetic cause at DIRAS1 gene. The affected dogs developed myoclonic seizures at young age - on average 6 months old - and seizures occur typically at rest. In some of the dogs the seizures could be triggered by light. The canine myoclonic epilepsy resembles human juvenile myoclonic syndrome in many aspects and the study has therefore meaningful implications for epilepsy research across species, says Professor Hannes Lohi from the canine gene research group, University of Helsinki. more

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