Saturday, December 9, 2017

Parasitic eye infection poses significant threat to UK dogs and may have implications for other UK animal, human populations.

Parasitic eye infection poses significant threat to UK dogs and may have implications for other UK animal, human populations.A parasitic worm that is becoming increasingly common in Europe poses a significant threat to UK dogs, warn experts in a new report. A research team, led by John Graham-Brown at the University of Liverpool, describe three cases in UK dogs with recent history of travel to mainland Europe. They call for vigilance when examining travelled dogs and warn that other animals -- and people -- should also be considered at risk of infection when travelling to areas where the parasite is endemic. Thelazia callipaeda is a parasitic worm capable of infecting a range of mammalian host species including dogs, cats and human beings. The worm is found in a species of fruit fly known to be present in the UK. The researchers believe the introduction of this species is a potential risk. Adult worms live in the eyes and associated tissues. Infected animals show a variety of symptoms, from mild conjunctivitis to severe corneal ulceration which, if untreated, can lead to blindness.

Curcumin offers potential therapy for cancers caused by HPV.

Curcumin offers potential therapy for #cancers caused by HPV. Curcumin, an antioxidant found in the curry spice turmeric, has been found to slow or limit the activity of the HPV virus, which causes oral and cervical cancers. Turmeric -- the familiar yellow spice common in Indian and Asian cooking -- may play a therapeutic role in oral cancers associated with human papillomavirus, according to new research published in ecancermedicalscience. One of the herb's key active ingredients -- an antioxidant called curcumin -- appears to have a quelling effect on the activity of human papillomavirus (HPV). HPV is a virus that promotes the development of cervical and oral cancer. There is no cure, but curcumin may offer a means of future control. The research indicates that curcumin turns down the expression of HPV in infected oral #cancer cells by downregulating the levels of cellular transcription factors AP-1 and NF-kB. These findings could suggest a new therapeutic role for curcumin in cancer control. #cancer

RESEARCH: Curcumin may help overcome drug-resistant tuberculosis.

RESEARCH: Curcumin may help overcome drug-resistant tuberculosis. Curcumin may help overcome drug-resistant tuberculosis.New research indicates that curcumin -- a substance in turmeric that is best known as one of the main components of curry powder -- may help fight drug-resistant tuberculosis. RESEARCH: Curcumin may help overcome drug-resistant tuberculosis. In Asia, turmeric is used to treat many health conditions and it has anti-inflammatory, antioxidant, and perhaps even anticancer properties. Investigators found that by stimulating human immune cells called macrophages, curcumin was able to successfully remove Mycobacterium tuberculosis, the causative bacterium of tuberculosis, from experimentally infected cells in culture. The process relied on inhibiting the activation of a cellular molecule called nuclear factor-kappa B. The ability of curcumin to modulate the immune response to Mycobacterium tuberculosis points to a potential new tuberculosis treatment that would be less prone to the development of drug resistance.

Agro-Veterinary Medicine : Research on how to fight Tuberculosis.

RESEARCH: How To Fight Tuberculosis. 

Tuberculosis is one of the most widespread life-threatening infectious diseases. Not only does antibiotic resistance make treatment increasingly difficult, but the bacteria's relatively impermeable mycomembrane also limits the effectiveness of many drugs. 


  In search of new antibiotics, researchers have developed a structural analogue of mycolic acid, the essential membrane building block. This drug blocks key enzymes used in mycomembrane biosynthesis, significantly increasing the effectiveness of conventional antibiotics.

Four in hospital isolation after contracting anthrax.

Four in hospital isolation after contracting anthrax. Four people have been put in an isolation ward at Mt Kenya Hospital Nyeri after been suspected to be infected with anthrax. Nyeri Central sub-county commissioner John Marete said the two brothers and their two neighbours from Thunguma village are reported to have eaten uninspected meat in Ruiru, Kiambu County before travelling to Nyeri on Friday. Mr Marete confirmed that the patients presented themselves at Nyeri Referral Hospital on Saturday morning and were immediately transferred to the health facility after screening. “They went to the county hospital in the morning and were immediately transferred to Mt Kenya hospital. They are receiving treatment at an isolation room since Anthrax is a contagious disease,” said Mr Marete.

Thursday, December 7, 2017

Flu outbreak reduces boar semen quality.

Flu outbreak reduces boar semen quality.An accidental outbreak of influenza A virus has been demonstrated to reduce semen quality in boars, US researchers found.The researchers, attached to Purdue University in Indiana, United States, found this out when an influenza outbreak occurred at the university’s swine barn, resulting in the infection of 28 boars with influenza A virus (H3N2) and causing the death of 2 boars. The article describes how the 28 boars, about 35 weeks of age, were enrolled in a study for semen quality parameters at the time of the outbreak. This allowed the researchers to describe the effects of the unintended influenza outbreak on sperm production, they wrote in the publication. They described how the first observation of mild clinical signs of illness (intermediate coughing and lethargy) in 3 boars occurred in April 2016, 3 weeks into the evaluation of semen quality.

Human hookworm infection exerts high health and economic burden.

Human hookworm infection exerts high health and economic burden. A new study suggests that the health and economic burden of hookworm infection is estimated to exceed those of a number of diseases receiving greater attention and investment. Researchers found that human hookworm infection confers a substantial global health and economic burden through loss of productivity, and years of life living with disability due to infection outcomes. Hookworm affects approximately 500 million people worldwide, yet its global economic and health impact is not well understood. While hookworm infection rarely results in death, it can lead to iron-deficiency anemia and malnutrition. Chronic health problems resulting from these conditions include lethargy, impaired physical and cognitive development, and adverse pregnancy outcomes.

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