Vaccination in cats with non adjuvanted vaccines protect against vaccination site sarcoma.(VSS)

Injections may be more dangerous for cats than for dogs. This may be because some pet vaccines and drugs contain substances called adjuvants to make them more effective. Adjuvants may be chemicals, parts of microbes or mammalian proteins that may overly irritate a cat's body. Adjuvants are safe for dogs, people and other pet species,but injections containing adjuvants may be the cause of a type of malignant tumor called "vaccine site sarcoma" (VSS).Vaccines containing small amounts of live viruses are among the most powerful in causing the immune system to create virus-battling antibodies. The immune system also modifies cells to aid in the fight against a virus when exposed to a live form. Some forms of live viruses in vaccines can infect pets so to avoid this problem and protect immune systems, veterinarians often use vaccines that are based on weaker killed or modified viruses. Another modified live-virus vaccine. Manufacturers boost the efficacy of vaccines containing modified viruses by adding adjuvants. Adjuvants are materials added to vaccines ,with the function of keeping the vaccine within the skin for a period of time after the vaccine is administered thus allowing the immune system to be properly stimulated. Adjuvants can also directly stimulate the immune system,although certain cats are genetically predisposed to forming VSS. Its documented that out of every 10,000 cats injected with a vaccine containing an adjuvant, only one to two develop cancerous tumors at the injection site. Cats will commonly develop a lump at the site of a vaccination, typically caused by inflammation and local immune stimulation. These lumps are benign and will resolve spontaneously a few weeks after they are evolve. A pet owner whose cat receives an adjuvanted injection should monitor the injection site for about three months, but cat -parent should visit a veterinarian if swelling grows progressively larger by a month following injection. It is recommended to visit the vet for a biopsy if 1) the lump is still present 3 months from the time of vaccination, 2) the lump is greater than 2 cm in diameter regardless of the duration of time of the vaccination. 3) the lump progressively increases in size over the course of one month since the time it was discovered. The strict compliance to the specific protocols regarding where vaccines should be administered is also important to prevent adverse reactions. The following depicts correct sites for the necessary vaccinations in cat; 1) rabies vaccines should be given as far down on the right hind limb . 2) feline leukemia vaccines should be given as far down on the left hind limb . 3) other vaccines should be given as far down on the right front leg . Vaccinations should never be given between the shoulder blades.