Friday, January 29, 2016

PORCINE HEALTH.

PREVENTION OF MASTITIS USING FEED ADDITIVES.

The need to fight mastitis with a reduced amount of antibiotics is growing. Certain supplements, when applied to cow diets can reduce somatic cell counts and hence mastitis incidence.one of these additives, based on 1-monoglycerides of a medium chain fatty acid. One of the most common and most costly health disorders in dairy cows is mastitis. Dairy farmers need to maintain udder health and milk quality as these parameters directly affect farm profitability. A lot of research has been conducted worldwide to gain insights in how to fight mastitis. Despite all the research done and tools to fight mastitis, there are still farms all over the world that have structural problems with this disease. While antibiotics are still widely used to counter mastitis, there is a growing demand to reduce the use of antibiotics. Non-antibiotic tools to fight mastitis can be found in feed supplements. Mastitis is an inflammation of the mammary gland and is characterized by an increased somatic cell count (SCC) in the milk. In the case of clinical mastitis, abnormal milk is detected, whereas in sub clinical mastitis, the milk composition is changed without visually detectable changes. Mastitis is caused by different strains of bacteria that enter the udder. Inside the udder the bacteria will multiply and cause inflammation. Staphylococcus and Streptococcus, both gram-positive bacteria, are probably the most common bacteria causing mastitis. Mastitis results in major economic losses. In general, the overall milk production and milk quality deteriorates. Treatment of mastitis will result in additional veterinary costs. The milk from cows treated with antibiotics will be discarded due to the withdrawal period of antibiotics. In some countries it is even common that the milk price will be reduced in case of a somatic cell count above a certain limit. Moreover, premature culling of cows results in additional losses as well. Furthermore, addressing mastitis problems give rise to extra labour costs and is time consuming. A lot of solutions have been suggested to reduce mastitis incidence in dairy cows. Besides maintaining good hygiene in the stable and milking house, improvement of udder health will be one of the key aspects to avoid mastitis problems. The company FRAmelco has developed the product FRA® Udder Health dry (hereafter called 'solution'), based on a new molecule, that can lower the somatic cell counts in milk when applied over a longer period of time. The product is a combination of α-monolaurin, a zinc product and micro-ingredients. The rumen-protected α-monolaurin, the main active component in the solution, is a 1-monoglyceride of lauric acid. 1-Monoglycerides of medium chain fatty acids are known to inhibit gram-positive pathogenic bacteria, like Staphylococcus and Streptococcus, which are known to cause mastitis. The zinc in the solution is a nano-sized zinc embedded in a matrix of medium chain fatty acid salts. This coating technique and coating material ensure stability during feed processing and the preparation of the total mix ration (TMR). The interaction with other components will not occur as the minerals remain protected inside the fat matrix until they reach the beginning of the small intestine. Zinc is known as an essential trace element and is especially important for the defense mechanism against pathogens in the udder. This is explained by the fact that zinc is required for the formation of keratin. Keratin is present in the teat canal and inhibits penetration of bacteria. In addition, keratin is important for the functioning of macrophages, which are cells present in the udder and are involved in the protection against pathogens in the mammary gland.

PROBIOTICS AND PREVENTION OF MASTITIS.

A new research shows that the cow’s own lactic acid bacteria, isolated from the bacteria in the mammary gland, could serve as a tool to prevent and/or treat mastitis. Bovine mastitis is a costly disease in dairy cattle worldwide. Currently, the control of bovine mastitis is mostly based on prevention by thorough hygienic procedures during milking. Additional strategies include vaccination and utilization of antibiotics. Despite these measures, mastitis is not fully under control, thus prompting the need for alternative strategies. One alternative is the emerging concept of mammary probiotics. For this purpose, lactic acid bacteria (LAB) are good candidates due to their Generally Recognised As Safe (GRAS) status and their recognized technological and inhibitory properties. LAB have been investigated for many years for their beneficial effects on human health. Likewise, the use of probiotics has gained interest in the veterinary community. the treatment of bovine mastitis is predominantly based on antibiotics. However, they are not totally effective and contribute to the emergence and transmission of antibiotic resistance within the host microbiota. There is thus a need for alternative strategies. story source; global diary.net

THE ZIKA VIRUS# MICROCEPHALY.

The Zika virus is "spreading explosively" in the Americas and the region may see up to four million cases of the disease strongly suspected of causing birth defects, the World Health Organization . The Zika virus, unlike other mosquito-borne viruses such as dengue, is relatively unknown and unstudied. That is set to change since Zika, now spreading through Latin America and the Caribbean, has been associated with an alarming rise in babies born in Brazil with abnormally small heads and brain defects -- a condition called microcephaly. Since the Zika outbreak began in northeastern Brazil last spring, an estimated 500,000 to 1.5 million people have been infected. The resulting illness only lasts a few days. The symptoms, including a rash, joint pains, inflammation of the eyes and fever, tend to be less debilitating than those of dengue. As many as 80 percent of infected people may be asymptomatic. It was not until months after Zika cases showed up in Brazil that a spike in microcephaly births was tied to women infected during pregnancy. More than 3,500 microcephaly cases have been reported since October in Brazil, compared to around 150 cases in 2014. While Zika's connection to microcephaly has yet to be definitively proven, the presence of the virus has been found in the bodies of five of the newborns that died with the condition and in the placentas of two women who miscarried babies with microcephaly.

THE ZIKA VIRUS.

On Monday (Jan. 25), the World Health Organization announced that Zika virus, a mosquito-borne illness that in the past year has swept quickly throughout equatorial countries, is expected to spread across the Americas and into the United States. Zika virus is transmitted by the mosquito species Aedes aegypti, also a carrier of dengue fever and chikungunya, two other tropical diseases. Though Aedes aegypti is not native to North America, researchers at the University of Notre Dame who study the species have reported a discovery of a population of the mosquitoes in a Capitol Hill neighborhood in Washington, D.C. , the team identified genetic evidence that these mosquitoes have overwintered for at least the past four years, meaning they are adapting for persistence in a northern climate well out of their normal range. This mosquito is typically restricted to tropical and subtropical regions of the world and not found farther north in the United States than Alabama, Mississippi, Georgia and South Carolina. What this means for the scientific world," said Severson, who led the team, "is some mosquito species are finding ways to survive in normally restrictive environments by taking advantage of underground refugia. Therefore, a real potential exists for active transmission of mosquito-borne tropical diseases in popular places like the National Mall.(source ;science daily) The emergence of mosquitoes in normally restricted areas has exposed the pandemic potential of the ZIKA VIRUS,with pregnant women at highest risk.Prevention of mosquito bites through use of treated nets,insecticides,and clearing environment of stagnant water,destruction of developmental stages and more recently the introduction of genetically modified mosquitoes to wipe out the infective strains have all been employed to reduce disease incidence. Travelling to zika-risk zones by pregnant women has also been initiated as they are mostly prone to the infection.

FIBER RICH DIET REDUCES RISK OF LUNG DISEASE.

A diet rich in fiber may not only protect against diabetes and heart disease, it may reduce the risk of developing lung disease, according to new research. "Lung disease is an important public health problem, so it's important to identify modifiable risk factors for prevention," said lead author Corrine Hanson PhD, RD, an associate professor of medical nutrition at the University of Nebraska Medical Center. "However, beyond smoking very few preventative strategies have been identified. Increasing fiber intake may be a practical and effective way for people to have an impact on their risk of lung disease." Analyzing data from the National Health and Nutrition Examination Surveys, researchers report in "The Relationship between Dietary Fiber Intake and Lung Function in NHANES," that among adults in the top quartile of fiber intake: • 68.3 percent had normal lung function, compared to 50.1 percent in the bottom quartile. • 14. 8 percent had airway restriction, compared to 29.8 percent in the bottom quartile. In two important breathing tests, those with the highest fiber intake also performed significantly better than those with the lowest intake. Those in the top quartile had a greater lung capacity (FVC) and could exhale more air in one second (FEV1) than those in the lowest quartile. Researchers reviewed records of 1,921 adults, ages 40 to 79, who participated in NHANES during 2009-2010. Administered by the Centers for Disease Control and Prevention, NHANES is unique in that it combines interviews with physical examinations. Fiber consumption was calculated based on the amount of fruits, vegetables, legumes and whole grains participants recalled eating. Those whose diets included more than 17.5 grams of fiber a day were in the top quartile and represented the largest number of participants, 571. Those getting less than 10.75 grams of fiber a day were in the lower group and represented the smallest number of participants, 360. Fiber-rich diet has been linked to healthy life style free of risk of heart disease,diabetes,colon cancer and bowel diseases emanating from constipation.This new research (according to American Thoracic Society) sheds light on how fiber reduces risk of lung diseases,further reinforcing the need to include more vegetables,fruits,nuts,oatmeal and other fiber rich sources to our menu. The benefits of fiber-rich meals also has the same results in animals, incorporating vegetables,oatmeal and fruits into their meal has been known to reduce risk of cancer, constipation and as a treatment protocol for diabetic patients and also prevention of diabetes in animals.

Sunday, January 24, 2016

Antimicrobial resistance :rats a major link in antimicrobial resistance in animals and man.

The world is faced with the issue of drug-resistance, super bugs and antibiotic residue in animal-by-products,forcing producers to look critically at methods of production and handling of products to resolve these issues. 

The war against super bugs is super hot with various school of thoughts proposing various theories and solutions to resolve the issue to ensure better health for man and the food animals consumed. The environment has been know to play host to various disease agents and the host/carriers are also housed in the environment,creating an unending cycle of infection to diverse hosts. 


 Rats are ubiquitous,with the propensity to carry disease agents in their urine,feces,hair and feet.These creatures could actually be the missing link in the antibiotic resistance saga. 

 Rats presence in poultry houses,farms and pet homes result in feed/water contamination with urine/feces resulting in salmonellosis,which the farmer responds to using antibiotics. When the source of infection is not removed, there will be a continuous cycle of infection-reinfection and treatment with various antibiotics .

  The threat of rats to health of man and animals is real and must be properly understood to ensure the necessary strategy is incorporated. A recent study by scientist in the University of Colombia, has revealed the risk that rats pose:Rats can absorb disease agents from their local environment and spread them, according to a University of British Colombia new study. The results also indicate that the threat rats pose to the health of poultry and humans has been underestimated.

Researchers studied the feces of rats caught at an Abbotsford, B.C. poultry farm, and discovered they all carried avian pathogenic E. coli, a bacteria with the ability to cause disease in chickens and potentially humans. More than one quarter of the rats were carrying multi-drug resistant strains of the bacteria. 

The findings support lead author Chelsea Himsworth's theory that rats act as a "pathogen sponge," soaking up bacteria from their environment. If rats can absorb pathogenic E. coli, then they could potentially be a source of all sorts of other pathogens that we have not anticipated," said Himsworth, assistant professor in the UBC School of Population and Public Health and leader of the Vancouver Rat Project, a group aiming to address the knowledge gap about the health threats associated with rats. 

 Himsworth was surprised to find that the E. coli strains carried by the farm rats were very similar to those found in chickens, and totally different from E. coli strains found in urban rats. Basically, the rural rat gut looked like the poultry gut, and nothing like the urban rat gut . 

 This latest study follows previous research by Himsworth that found human pathogens, including MRSA (methicillin-resistant Staphylococcus aureus) and C. difficile, in the feces of rats in Vancouver's Downtown Eastside. 

 Rat infestations ought to be taken seriously," said Himsworth. "They need to be tackled with an educated, informed approach in collaboration with scientists and pest control professionals. There should be the development of municipal programs for managing rat infestations and rat-related issues. 

 Rodent control # rodenticide rodent bait # rodent proof.

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