PREVENTION OF MASTITIS USING FEED ADDITIVES.

The need to fight mastitis with a reduced amount of antibiotics is growing. Certain supplements, when applied to cow diets can reduce somatic cell counts and hence mastitis incidence.one of these additives, based on 1-monoglycerides of a medium chain fatty acid. One of the most common and most costly health disorders in dairy cows is mastitis. Dairy farmers need to maintain udder health and milk quality as these parameters directly affect farm profitability. A lot of research has been conducted worldwide to gain insights in how to fight mastitis. Despite all the research done and tools to fight mastitis, there are still farms all over the world that have structural problems with this disease. While antibiotics are still widely used to counter mastitis, there is a growing demand to reduce the use of antibiotics. Non-antibiotic tools to fight mastitis can be found in feed supplements. Mastitis is an inflammation of the mammary gland and is characterized by an increased somatic cell count (SCC) in the milk. In the case of clinical mastitis, abnormal milk is detected, whereas in sub clinical mastitis, the milk composition is changed without visually detectable changes. Mastitis is caused by different strains of bacteria that enter the udder. Inside the udder the bacteria will multiply and cause inflammation. Staphylococcus and Streptococcus, both gram-positive bacteria, are probably the most common bacteria causing mastitis. Mastitis results in major economic losses. In general, the overall milk production and milk quality deteriorates. Treatment of mastitis will result in additional veterinary costs. The milk from cows treated with antibiotics will be discarded due to the withdrawal period of antibiotics. In some countries it is even common that the milk price will be reduced in case of a somatic cell count above a certain limit. Moreover, premature culling of cows results in additional losses as well. Furthermore, addressing mastitis problems give rise to extra labour costs and is time consuming. A lot of solutions have been suggested to reduce mastitis incidence in dairy cows. Besides maintaining good hygiene in the stable and milking house, improvement of udder health will be one of the key aspects to avoid mastitis problems. The company FRAmelco has developed the product FRA® Udder Health dry (hereafter called 'solution'), based on a new molecule, that can lower the somatic cell counts in milk when applied over a longer period of time. The product is a combination of α-monolaurin, a zinc product and micro-ingredients. The rumen-protected α-monolaurin, the main active component in the solution, is a 1-monoglyceride of lauric acid. 1-Monoglycerides of medium chain fatty acids are known to inhibit gram-positive pathogenic bacteria, like Staphylococcus and Streptococcus, which are known to cause mastitis. The zinc in the solution is a nano-sized zinc embedded in a matrix of medium chain fatty acid salts. This coating technique and coating material ensure stability during feed processing and the preparation of the total mix ration (TMR). The interaction with other components will not occur as the minerals remain protected inside the fat matrix until they reach the beginning of the small intestine. Zinc is known as an essential trace element and is especially important for the defense mechanism against pathogens in the udder. This is explained by the fact that zinc is required for the formation of keratin. Keratin is present in the teat canal and inhibits penetration of bacteria. In addition, keratin is important for the functioning of macrophages, which are cells present in the udder and are involved in the protection against pathogens in the mammary gland.