AGRIBUSINESS: Expanding the reach of flavour imprinting in piglets.

AGRIBUSINESS: Expanding the reach of flavour imprinting in piglets. An aroma, based on essential oils, is capable of generating an imprinting effect in piglets that can boost their introduction to solid feed after weaning and improves their performance. Combining this with spray dried porcine plasma could bring even further benefits post-weaning. Early weaned piglets are subject to a great deal of stress and have to adapt abruptly to a new diet, which delivers a great physiological challenge. As a result, during the first week after weaning, piglets typically have a low feed intake and a growth decrease that has an impact on the animal’s gut morphology, increasing the risk of post-weaning diarrhoea and consequently affecting the animals subsequent performance. Supplementing sow and post-weaning diets with Print-Arome, a flavour formulated with essential oils, has an imprinting effect in piglets. This effect familiarises the piglets with its scent and facilitates the introduction to solid feed. The transfer of dietary information from mother to offspring with the essential oils flavour has been proven to successfully improve feed intake and weight gain of piglets at weaning. Likewise, spray dried porcine plasma (SDPP) is also a common feed ingredient used for similar objectives; included in weaning diets to improve feed intake, post-weaning performance and reduce diarrhoea incidence.

Agribusiness: A good start is vital for healthy piglets.

Agribusiness: A good start is vital for healthy piglets.Raising healthy piglets from start through weaning is a challenge not to be underestimated, impacting performance and health at later stages. Sudden change in dietary regimens and management at weaning puts a heavy burden on the animal’s immature digestive system. This leads to a disturbed immune system and microbiota, and increased susceptibility to diseases. Stress already starts at birth, a crucial period filled with risks: piglets must be born strong and healthy and remain that way. Once born, piglets encounter several hurdles: piglets suffer from all kinds of pathogenic challenges with an immature immune system. There is a significant and immediate demand on the gut to digest and absorb nutrients efficiently to maintain a high growth rate. Intestinal epithelial cell integrity is of prime importance considering that this epithelium is responsible for absorption of water, electrolytes, and nutrients. Not to forget the beneficial microbiome that must establish itself as soon as possible to guarantee a fully functioning intestinal tract. Once the piglet could manage these hurdles, another event, considered as a major stressor, takes place: weaning. Although technological improvements in housing, nutrition, and management are available to minimise the stress, piglets are weaned at unphysiologically early ages. The sudden change in dietary regimens at weaning places a heavy burden on the immature digestive system of the piglet. The gastro-intestinal tract is affected by a change in microbiome, mechanical damage, and inflammation as reaction to the stresses (social, nutritional, handling) of weaning. The effects are aggravated by the immature immune system which has not developed a full response to cope with pathogens, resulting in disease . It is clear impairment of the normal gut and immune function, leading to diarrhoea and even death, which needs to be avoided.

AGRIBUSINESS: 4 piglet parameters for lifetime performance.

             AGRIBUSINESS: 4 piglet parameters for lifetime performance.

 Genetic selection is leading to larger litters of piglets born with lowered levels of physiological maturity. As this trend amplifies an evolutionary strategy in swine favouring survival of the fittest, it presents negative performance and animal welfare implications.

 Sow Peripartal Syndrome is a complex web of interactions affecting sows and piglets during the peripartal period. At least four parameters are present at birth that can ultimately determine piglets’ lifetime performance.

The following is an update on research underway to managing the syndrome. Alive at birth While genetic selection has increased the total number of pigs per litter, the number of pigs born alive has not increased at the same pace.

AGRIBUSINESS: Heat stress in pigs and its effect on the gut.

AGRIBUSINESS:    Heat stress in pigs and its effect on the gut. 


 Heat Stress is a physiological response to high environmental temperatures, where the animal is out of its thermo-neutral zone and can no longer effectively regulate its body temperature. Consequently, animal health, well-being and performance are negatively affected.

 

VETERINARY MEDICINE: Seizures in Dogs.

 Seizures in Dogs. A seizure is a sudden episode of abnormal brain activity that often involves some loss of body control.

Some dogs begin to act strange before a seizure begins and may become anxious or restless.
Some may stagger, appear disoriented, or exhibit other abnormal behaviors.
 This period, which precedes the seizure, usually lasts a few minutes and is called the aura phase.

The seizure itself often manifests as full body convulsions or small, localized spasms that may last from a few seconds to a few minutes.


  FORMS OF SEIZURES.

 1) Generalized or grand mal seizures.

 2)Focal seizures.

3)Psycho-motor seizures.

 4)Cluster seizures.

Generalized or grand mal seizures: usually involve the entire body. A dog suffering a grand mal seizure may fall over, become stiff, and shake its whole body violently. Many dogs salivate or foam at the mouth, and some urinate and/or defecate involuntarily. Dogs may vocalize as well, whining and growling during a seizure.

 Focal seizures: the least serious type, are limited to a specific part of the body and may not look like much more than a twitch in the dog's facial muscles or limbs.

 Psychomotor seizures: are characterized by odd behavior that lasts only a minute or two. For example, your dog may suddenly start chasing its tail or acting as if it sees things that aren't really there.

 Cluster seizures: which are a more serious type, are distinguished by multiple seizures over the course of 24 hours.

 CAUSES OF SEIZURES.

 1)An environmental allergy could be responsible. Usually, removing the allergen from the dog's environment will prevent this type of seizure from recurring.

 2) Some viral or bacterial infections may cause seizures in dogs. These are typically treated with antiviral or antibiotic medications.

 3)The most common cause of seizures in canines is known as idiopathic epilepsy. It's believed that most dogs with this condition inherit it, but what causes it is still not clear. However, this type of seizure usually presents at times when the dog's brain activity is shifting from one mode to another (such as between sleep and wakefulness)

. 4) A brain tumor, whether it's malignant or benign, may also cause convulsive seizures in a dog. 

Treatment / Prevention: If your dog has had seizures before and you think one is coming on, try to move the dog to a safe, soft area where there are no sharp objects or hard floors.

 The best thing you can do is to remain calm and try to keep your dog and yourself out of danger. Never put your hands near or in your dog's mouth during a seizure.

 Seizures in dogs can often be regulated with medications and/or lifestyle changes.

 There are several anticonvulsant medications that are used to control your dog's seizures.Most vets won't recommend pharmaceutical treatment if the seizures occur less often than once a month or if they're very mild.  A visit to your vet is necessary.

AGRIBUSINESS: Hens that lay human proteins in eggs offer future therapy hope..

AGRIBUSINESS: Hens that lay human proteins in eggs offer future therapy hope.Chickens that are genetically modified to produce human proteins in their eggs can offer a cost-effective method of producing certain types of drugs, research suggests. The study -- which has initially focused on producing high quality proteins for use in scientific research -- found the drugs work at least as well as the same proteins produced using existing methods. High quantities of the proteins can be recovered from each egg using a simple purification system and there are no adverse effects on the chickens themselves, which lay eggs as normal. Researchers say the findings provide sound evidence for using chickens as a cheap method of producing high quality drugs for use in research studies and, potentially one day, in patients. Eggs are already used for growing viruses that are used as vaccines, such as the flu jab. This new approach is different because the therapeutic proteins are encoded in the chicken's DNA and produced as part of the egg white.

RESEARCH: New skin test detects prion infection before symptoms appear.

RESEARCH: New skin test detects prion infection before symptoms appear. Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease (CJD) in humans, mad cow disease in cattle, and chronic wasting disease in elk and deer. The infectious, misfolded protein particles often go undetected as they destroy brain tissue, causing memory loss, mobility issues, and ultimately death. Preclinical detection of prions has proven difficult, but new research suggests skin samples hold early signs of prion disease that precede neurologic symptoms. Currently, a definitive diagnosis of Creutzfeldt-Jakob disease is dependent on the examination of diseased brain tissue obtained at biopsy or autopsy. It has been impossible to detect at the early preclinical stage," said Wenquan Zou, MD, PhD, associate professor of pathology at Case Western Reserve University School of Medicine. In a ground-breaking study published in Nature Communications, Zou and an international team of researchers successfully used two methods to detect prions in skin samples collected from inoculated rodents. The study provides the first proof-of-concept evidence that readily accessible skin samples could be used to detect prion disease early -- before clinical symptoms appear. In the new study, Zou and colleagues successfully detected prions in rodent skin samples as early as two weeks post-infection. They also detected prions in the skin of uninoculated rodents that were housed alongside inoculated cage mates, demonstrating that prion transmission can occur between cohabiting rodents.