Agribusiness: A good start is vital for healthy piglets.

Agribusiness: A good start is vital for healthy piglets.Raising healthy piglets from start through weaning is a challenge not to be underestimated, impacting performance and health at later stages. Sudden change in dietary regimens and management at weaning puts a heavy burden on the animal’s immature digestive system. This leads to a disturbed immune system and microbiota, and increased susceptibility to diseases. Stress already starts at birth, a crucial period filled with risks: piglets must be born strong and healthy and remain that way. Once born, piglets encounter several hurdles: piglets suffer from all kinds of pathogenic challenges with an immature immune system. There is a significant and immediate demand on the gut to digest and absorb nutrients efficiently to maintain a high growth rate. Intestinal epithelial cell integrity is of prime importance considering that this epithelium is responsible for absorption of water, electrolytes, and nutrients. Not to forget the beneficial microbiome that must establish itself as soon as possible to guarantee a fully functioning intestinal tract. Once the piglet could manage these hurdles, another event, considered as a major stressor, takes place: weaning. Although technological improvements in housing, nutrition, and management are available to minimise the stress, piglets are weaned at unphysiologically early ages. The sudden change in dietary regimens at weaning places a heavy burden on the immature digestive system of the piglet. The gastro-intestinal tract is affected by a change in microbiome, mechanical damage, and inflammation as reaction to the stresses (social, nutritional, handling) of weaning. The effects are aggravated by the immature immune system which has not developed a full response to cope with pathogens, resulting in disease . It is clear impairment of the normal gut and immune function, leading to diarrhoea and even death, which needs to be avoided.