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Wednesday, February 17, 2016
PREVENTION AND TREATMENT OF SUN BURN IN ANIMALS.
Animals should have a shady place to lie in. Especially at midday, when the sun is at its strongest and presents the greatest risk, not just for the skin but for the animal overall”, explains dermatologist Horvath-Ungerböck. Particularly sensitive animals require sun protection in the form of a waterproof sunscreen with an SPF of at least 30 or a sunblock containing zinc oxide, for example.
Some illnesses and genetic defects that result in a thin coat can make the skin more sensitive to sunburn. Any longer-term stimulus that results in a loss of fur is a possible factor. These can include parasitic infections, chronic skin conditions, or congenital hairlessness. In some cases, exposure to the sun can worsen an existing condition. Animals with autoimmune skin diseases must be carefully protected from the sun, for example. And areas of the skin that were covered by fur but are suddenly exposed due to hair loss, such as scar tissue after an operation or injury, should be carefully observed and shielded as needed.
For longer hikes through the mountains where the sun’s rays are particularly aggressive, sensitive animals should wear a t-shirt, coat or hat for protection. The skin specialist advises owners not to worry: “Not every white dog or white cat needs sunscreen or clothing to protect it from the sun. If sun damage has already occurred though, or if an animal is highly sensitive, it is up to us to protect it from further damage.
In animals, sunburn results in an acute inflammation of the skin that can cause itching or even pain, depending on the individual animal. Frequent sunburns can lead to pre-cancerous conditions or even actual skin tumours. sometimes squamous cell carcinoma on the heads of white, outdoor cats as the result of chronic sun exposure. The affected areas of the skin then need to be surgically removed.
If sunburn is visible as reddened, warm or flaking skin, the animal should be moved to the shade as quickly as possible. Cool compresses and ointments to soothe the skin can help relieve the initial symptoms. If the burn is severe, a veterinarian should be consulted as treatment with a cortisone product may be indicated to prevent inflammation. If the skin changes present as a secondary infection, antibiotics may be indicated. The affected animal will need to be well protected from the sun in future to prevent permanent damage.
story;culled from science daily.

SUN BURN IN ANIMALS.
Some dogs and cats prone to sunburn.
Excessive sunbathing damages the skin. Humans are not the only ones who need to monitor their exposure to UV rays: animals are at risk too. Dogs and cats with white or thin coats are at particular risk, as are animals with very closely shorn fur or with certain pre-existing conditions.
Excessive sunbathing damages the skin. Humans are not the only ones who need to monitor their exposure to UV rays: animals are at risk too. Dogs and cats with white or thin coats are at particular risk, as are animals with very closely short fur or with certain pre-existing conditions. Dermatologist Christa Horvath-Ungerböck from the University of Veterinary Medicine, Vienna explains which animals are particularly sensitive, how to prevent sun damage to the skin, and how to treat a sunburned animal.
Human or animals skin with little or no pigmentation is very sensitive to the sun in general. Hairless pets or pets with very short or thin fur can also be vulnerable. For dogs and cats this applies in particular to those parts of the skin that are regularly exposed to the sun. These include the ears, the bridge of the nose, the skin around the eyes, and the back. Some animals particularly enjoy lying on tHouse pets with white or short fur are at particular risk of sunburn.
The Dogo Argentino breed, white bulldogs, Dalmatians, boxers, whippets, beagles and white or multi-coloured cats with white patches have skin that is very sensitive to light, especially on their heads. In summer animals with short fur can also have a problem. The short hair allows UV rays penetrate down to the sensitive skin and cause sunburn.
Hairless dogs and cats are naturally more sensitive to the sun, since they lack the natural sun protection fur affords. Here too though, skin pigmentation plays a role, and darker animals are less vulnerable to UV rays. Owners of vulnerable breeds should take particular care to protect their animals from the sun and their backs to bask in the sun. This exposes the skin on their bellies, which is often hairless, to the rays of the sun, increasing the risk of sunburn.

Horse dung has scientists on scent of antibiotic success
The key to creating the next generation of antibiotics could lie in horse dung. That's according to researchers at ETH Zurich and the University of Bonn who have produced copsin, an antibiotic protein compound, in the common inky cap mushroom that grows in manure.
A new protein with antibiotic properties has been found in a mushroom that grows on horse dung. Researchers are now exploring the various potential applications.Microbiologists and molecular biologists at ETH Zurich and the University of Bonn have discovered a new agent in fungi that kills bacteria.
The substance, known as copsin, has the same effect as traditional antibiotics, but belongs to a different class of biochemical substances. Copsin is a protein, whereas traditional antibiotics are often non-protein organic compounds.
Copsin belongs to the group of defensins, a class of small proteins produced by many organisms to combat microorganisms that cause disease. The human body also produces defensins to protect itself against infections. They have been found, for example, on the skin and in the mucous membranes.
story from science daily.

Tuesday, February 16, 2016
Researchers identify potential approach to treat heart disease through the gut.
Researchers have demonstrated -- for the first time -- that targeting microbes in the gut may prevent heart disease brought on by nutrients contained in a diet rich in red meat, eggs and high-fat dairy products.
This novel approach centers around the research team's previous discovery that TMAO -- trimethylamine N-oxide, a byproduct formed in the gut during digestion of animal fats -- is linked to atherosclerosis and heart disease. Now, the team has identified a naturally occurring inhibitor called DMB -- 3,3-dimethyl-1-butanol, found in some cold-pressed extra virgin olive oils and grape seed oils -- that reduced levels of TMAO and reduced atherosclerosis in mice.
This discovery may represent a potential new therapeutic approach for the prevention of heart disease, the No. 1 killer , as well as other metabolic diseases linked to gut microbes, such as diabetes
culled from science daily.
Lactation, weather found to predict milk quality in dairy cows.
The quality of colostrum -- the nutrient-rich milk newborn dairy calves first drink from their mothers -- can be predicted by the mother's previous lactation performance and weather, according to new research
Colostrum is a concentrated source of nutrients, which includes fats, proteins, including immunoglobulins such as Immunoglobulin G (IgG), carbohydrates, vitamins, and minerals. It is key in supporting the health of the young dairy animal. Previous research has found that inadequate feeding of quality colostrum to newborn calves can result in reduced growth rates, increased risk of disease and death, increased risk of being culled, and decreased milk production in the first and second lactations.
UNH researchers found that previous lactation performance data can predict colostrum quality; the more lactations the cow has had in the past, the higher the quality of colostrum in the future. This method allows dairy producers to predict colostrum quality before the calf is born and the ability to estimate Immunoglobulin G content, which is the primary measure of colostrum quality, of the colostrum without having to collect it.
The long-term effects of colostrum determine the success of the cow, and therefore special care should be taken to ensure colostrum of the highest quality is provided to the newborn calf.Researchers also found that the poorest quality colostrum was produced during the winter. The researchers theorize that in warmer temperatures, the blood vessels of the cow dilate, causing them to be more permeable to IgG. This increased permeability of the blood vessels may lead to improved colostrum.It is apparent from these studies that environmental temperature or day length has an impact on colostrum quality .
culled from papers from university of Hampshire

Brain researchers demonstrate the importance of oral health in stroke.
A study of patients entering the hospital for acute stroke, researchers have increased their understanding of an association between certain types of stroke and the presence of the oral bacteria (cnm-positive Streptococcus mutans).
In the single hospital study, researchers at the National Cerebral and Cardiovascular Center in Osaka, Japan, observed stroke patients to gain a better understanding of the relationship between hemorrhagic stroke and oral bacteria. Among the patients who experienced intracerebral hemorrhage (ICH), 26 percent were found to have a specific bacterium in their saliva, cnm-positive S. mutans. Among patients with other types of stroke, only 6 percent tested positive for the bacterium.
Strokes are characterized as either ischemic strokes, which involve a blockage of one or more blood vessels supplying the brain, or hemorrhagic strokes, in which blood vessels in the brain rupture, causing bleeding.
The researchers also evaluated MRIs of study subjects for the presence of cerebral microbleeds (CMB), small brain hemorrhages which may cause dementia and also often underlie ICH. They found that the number of CMBs was significantly higher in subjects with cnm-positive S. mutans than in those without.
This study shows that oral health is important for brain health. People need to take care of their teeth because it is good for their brain and their heart as well as their teeth," Friedland said. "The study and related work in our labs have shown that oral bacteria are involved in several kinds of stroke, including brain hemorrhages and strokes that lead to dementia."
Multiple research studies have shown a close association between the presence of gum disease and heart disease, and a 2013 publication by Jan Potempa, Ph.D., D.Sc., of the UofL School of Dentistry, revealed how the bacterium responsible for gum disease worsens rheumatoid arthritis.
Excerpts from material from University of Louisville.

Microchip used to build a first-ever artificial kidney.
Nephrologists are making major progress on a first-of-its kind device to free kidney patients from dialysis. He is building an implantable artificial kidney with microchip filters and living kidney cells that will be powered by a patient's own heart.
Vanderbilt University Medical Center nephrologist and associate professor of medicine Dr. William H. Fissell IV, is making major progress on a first-of-its kind device to free kidney patients from dialysis. He is building an implantable artificial kidney with microchip filters and living kidney cells that will be powered by a patient's own heart.
"We are creating a bio-hybrid device that can mimic a kidney to remove enough waste products, salt and water to keep a patient off dialysis," said Fissell. Fissell says the goal is to make it small enough, roughly the size of a soda can, to be implanted inside a patient's body. The key to the device is a microchip.
"It's called silicon nanotechnology. It uses the same processes that were developed by the microelectronics industry for computers," said Fissell. The chips are affordable, precise and make ideal filters. Fissell and his team are designing each pore in the filter one by one based on what they want that pore to do. Each device will hold roughly fifteen microchips layered on top of each other. But the microchips have another essential role beyond filtering. "They're also the scaffold in which living kidney cells will rest," said Fissell.
Fissell and his team use live kidney cells that will grow on and around the microchip filters. The goal is for these cells to mimic the natural actions of the kidney and the device operates naturally with a patient's blood flow.
credit;Vanderbilt University.

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