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Showing posts with label inflammation. Show all posts
Showing posts with label inflammation. Show all posts
Friday, March 4, 2016
STRESS COULD BE DESTROYING YOUR BRAIN .
Stress destroys brain leading to memory loss,according to a research published in journal of neuroscience. Long-term stress can have lots of effects on the body—it can cause chronic muscle tension, heart problems, and fertility issues in both men and women. Now researchers have performed a new study in mice that they believe reveals another effect of chronic stress on the brain: Inflammation, which can lead to memory loss and depression.
In the study, the researchers stressed out several mice by periodically putting a much more aggressive mouse into their cage. After six days of exposure, the stressed mice could no longer recall the location of a hole to escape a maze, which they remembered easily before the stressful period began. "The stressed mice didn't recall it. The mice that weren't stressed, they really remembered it," said Jonathan Godbout, a neuroscience professor at Ohio State University and one of the study authors in a press release. For four weeks after the trauma, the mice continued to cower in corners, the mouse equivalent of social avoidance, a major symptom of depression.
The researchers suspected that the stress was affecting the mice’s hippocampi, a part of the brain key to memory and spatial navigation. They found cells from mice’s immune system, called macrophages, in the hippocampus, and the macrophages were preventing the growth of more brain cells. The stress, it seemed, was causing the mice’s immune systems to attack their own brains, causing inflammation. The researchers dosed the mice a drug known to reduce inflammation to see how they would respond. Though their social avoidance and brain cell deficit persisted, the mice had fewer macrophages in their brains and their memories returned to normal, indicating to the researchers that inflammation was behind the neurological effects of chronic stress.
This study points out the connection between chronic stress and memory loss, or between inflammation and depression. It provides a new, promising link between all four. That could help doctors prescribe more immune-focused treatments for conditions like anxiety and depression, some of which are being tested now, as the New Scientist reports.
read more here;http://www.popsci.com/chronic-stress-causes-inflammation-in-brain.
Wednesday, February 17, 2016
PREVENTION AND TREATMENT OF SUN BURN IN ANIMALS.
Animals should have a shady place to lie in. Especially at midday, when the sun is at its strongest and presents the greatest risk, not just for the skin but for the animal overall”, explains dermatologist Horvath-Ungerböck. Particularly sensitive animals require sun protection in the form of a waterproof sunscreen with an SPF of at least 30 or a sunblock containing zinc oxide, for example.
Some illnesses and genetic defects that result in a thin coat can make the skin more sensitive to sunburn. Any longer-term stimulus that results in a loss of fur is a possible factor. These can include parasitic infections, chronic skin conditions, or congenital hairlessness. In some cases, exposure to the sun can worsen an existing condition. Animals with autoimmune skin diseases must be carefully protected from the sun, for example. And areas of the skin that were covered by fur but are suddenly exposed due to hair loss, such as scar tissue after an operation or injury, should be carefully observed and shielded as needed.
For longer hikes through the mountains where the sun’s rays are particularly aggressive, sensitive animals should wear a t-shirt, coat or hat for protection. The skin specialist advises owners not to worry: “Not every white dog or white cat needs sunscreen or clothing to protect it from the sun. If sun damage has already occurred though, or if an animal is highly sensitive, it is up to us to protect it from further damage.
In animals, sunburn results in an acute inflammation of the skin that can cause itching or even pain, depending on the individual animal. Frequent sunburns can lead to pre-cancerous conditions or even actual skin tumours. sometimes squamous cell carcinoma on the heads of white, outdoor cats as the result of chronic sun exposure. The affected areas of the skin then need to be surgically removed.
If sunburn is visible as reddened, warm or flaking skin, the animal should be moved to the shade as quickly as possible. Cool compresses and ointments to soothe the skin can help relieve the initial symptoms. If the burn is severe, a veterinarian should be consulted as treatment with a cortisone product may be indicated to prevent inflammation. If the skin changes present as a secondary infection, antibiotics may be indicated. The affected animal will need to be well protected from the sun in future to prevent permanent damage.
story;culled from science daily.
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