Researchers identify potential approach to treat heart disease through the gut.

Researchers have demonstrated -- for the first time -- that targeting microbes in the gut may prevent heart disease brought on by nutrients contained in a diet rich in red meat, eggs and high-fat dairy products. This novel approach centers around the research team's previous discovery that TMAO -- trimethylamine N-oxide, a byproduct formed in the gut during digestion of animal fats -- is linked to atherosclerosis and heart disease. Now, the team has identified a naturally occurring inhibitor called DMB -- 3,3-dimethyl-1-butanol, found in some cold-pressed extra virgin olive oils and grape seed oils -- that reduced levels of TMAO and reduced atherosclerosis in mice. This discovery may represent a potential new therapeutic approach for the prevention of heart disease, the No. 1 killer , as well as other metabolic diseases linked to gut microbes, such as diabetes culled from science daily.