Calcium EDTA to Treat Lead Poison in Pets.

Edetate Calcium Disodium, also known as Calcium EDTA, is a chelating agent used by veterinarians to treat lead poisoning in dogs and cats. It is used to treat other types of heavy metal toxicity in animals . Animals can get lead poisoning just as humans by ingesting a large amount of lead-containing materials. Pets and other animals get lead from paint, plumbing materials, linoleum tiles, lead foil, solder, golf balls, drinking water from lead pipes, lead weights, newspaper, certain dyes, insulation and a host of other lead-containing products and materials. Lead poisoning can cause an animal to experience both neurological and gastrointestinal complications. Common neurological signs include seizures, blindness, running aimlessly, running in circles, ataxia and behavioral changes. Gastrointestinal problems can include abdominal pain, vomiting, lack of appetite and either constipation or diarrhea. - Ingestion of lead and other heavy metals displaces calcium in the body. Therefore, many veterinarians use chelation therapy to aid in eliminating the lead or heavy metals while increasing calcium levels throughout the body. Prior to the administration of Calcium EDTA therapy, the animal’s blood lead concentration levels will be tested and then monitored throughout the therapy until the lead level in the blood is normal. Calcium EDTA is administered subcutaneously and only in a veterinary office or animal hospital setting where blood monitoring can be conducted.Calcium EDTA should not be administered to an animal with a pre-existing kidney condition. In some cases, a second round of Calcium EDTA is required if the first therapy isn’t fully successful. If your pet experiences vomiting or diarrhea while undergoing Calcium EDTA therapy, the veterinarian may prescribe a zinc supplement because this medication chelates zinc in addition to lead. Contributed by :Giano Panzarella for diamondbackdrugs.

BOAR FEEDING AND REPRODUCTIVE HEALTH.

In pig farming the major aim is to produce large litter sizes that are healthy with high reproductive capacity.The success in pig farming is hinged on genetics as the pig cannot exceed the genetic capacity hence a good genetic line is chosen. Housing and management also influences the outcome of venture, proper housing and animal management is another crucial point. The major key to success is feeding programme,the animals must have access to good quality feed ,balanced and readily available. The importance of feed in the boar cannot be overemphasized as the quality of sperm produced will set the genetic track for the farm. When preparing the feed,you need to ensure that all ingredients that will ensure the following are available; proper muscle development, proper bone development and production of high quality and quantity of sperm. The feed should provide the necessary daily feed intake which must contain dietary energy and protein, additives and vitamins such as organic selenium, vitamin E, zinc, biotin, vitamin C. The breeding boars must be mature animals, so also must the to sows. An underweight or overweight boar or sow will often result in breeding failure,hence feeding should be monitored. Boar libido unlike sperm production, cannot be easily manipulated by changing dietary protein and energy levels but its a known fact only prolonged conditions of over-feeding or under-feeding, and excessive extreme cases of body condition change, can negatively impair boar libido. Scientific research proves that protein and amino acids lysine and methionine + cystine, play an important role in sperm production. In particular, the sulphur-containing amino acids methionine/cystine affect the secretory activity of the epididymis, thus significantly enhancing sperm volume. This effect is very marked in intensively used boars, where sperm production has been shown to be positively influenced when extra protein and methionine was added to the diet. Protein combined with adequate energy intake is very crucial for optimal sperm production.

Trace Mineral Nutrition in the Cow.

Mineral nutrition is vital to overall cow performance. Without an appropriate balance of minerals, cows may not perform as expected or could exhibit detrimental effects. Minerals are divided into two groups based on the quantity of the mineral required by the cow: macro minerals and trace minerals (micro minerals). The macro minerals are required as a percent of the diet, while the trace minerals are required in ppm (parts per million). There are six trace minerals of significant importance in a cow’s diet. These are cobalt (Co), copper (Cu), iodine (I), manganese (Mn), selenium (Se) and zinc (Zn). They each play important roles in the body and can have negative impacts if they are deficient or in excess. 1) Cobalt The requirement for Co is 0.10 ppm and is typically adequate in summer range and many silages, but can be deficient in low-quality forage (e.g., winter range, crop residue). Cobalt deficiency is characterized by depressed appetite, listlessness, decreased growth, reduced milk production and a rough hair coat. Cobalt is necessary for the rumen microbes to produce vitamin B12. Vitamin B12 is used by the rumen microbes in metabolic processes to produce propionate, which is a volatile fatty acid that provides energy to the cow. The cow does not readily absorb Co, but the rumen microbes use it for vitamin B12 synthesis. 2) Copper and molydenum Copper plays many important roles in the cattle’s systems, including red-blood cell health, collagen development, reproduction, and immunity. Not only does Cu play important roles by itself, but the combination of Cu, S, and Mo creates several important enzymes involved in nucleotide and vitamin metabolism. The challenge is ensuring that the Cu:Mo ratio is correct and will not cause a negative interaction. This ratio needs to be between 2:1 and 4:1. The cow’s requirement for Mo is very small and frequently met by forages in grazing cattle. Depending on soil type, Cu availability may be reduced, specifically in alkaline soils. Multiple minerals besides Mo and S can also interact and decrease Cu availability. These include zinc (Zn), iron (Fe), selenium (Se) or phosphorus (P). The forage Cu level may be adequate, however secondary deficiencies can occur as a result of increased levels of the minerals listed above, which can tie up Cu and make it unavailable to the cow. Cattle with a Cu deficiency are characterized as having a lighter colored hair or faded hair coat, reduced conception rates, severe diarrhea, brittle bones and reduced immune response. 3) Iodine The requirement for I is very low (0.5 ppm), however deficiencies are more prevalent than toxicities . Iodine plays a key role in maintaining metabolic rate by producing the hormone thyroxin from the thyroid gland. If I levels are low, thyroxin production is reduced and results in lower metabolic rates, that has a snowball effect on decreasing milk production, weaning weights and overall herd health. Cows that are deficient in I while they are pregnant can have calves that are born blind, weak, hairless or stillborn. Another symptom of deficiency is goiter, an enlargement of the thyroid gland. 4)Manganese Manganese plays an important role in growth and reproduction. The requirement for Mn in growing and finishing cattle is 20 ppm, while the requirement in pregnant and lactating cows is 40 ppm. Cattle have a high tolerance level for Mn, up to 1,000 ppm. However Mn interacts with other minerals so deficiency effects could be noticed at lower Mn levels. If Mn requirements are not met, the primary indicator will be reduced conception rates. Other indicators are poor growth rates, low birth weights and increased abortions 5)Zinc Zinc plays a role in immune response, enzyme systems and hoof health. The requirement is 30 ppm and forages, grains and proteins are all sources of Zn. Forages average 20 ppm Zn, grains are approximately 35 ppm Zn, and protein sources average between 60 to 70 ppm Zn. Therefore, if cattle are fed forage based diets, additional Zn supplementation may be necessary. Signs of Zn deficiency are reduced feed intake and weight gain, excessive salivation, rough hair coat and eventually swelling of the feet and legs. When it comes to supplementing trace minerals, providing a trace mineralized salt that contains Co, I, Cu, Mn and Zn is a good insurance policy for decreasing the occurrence of deficiencies. In certain situations, a trace mineralized salt will be adequate to alleviate mild deficiencies; however there are other situations when an additional mineral supplement will be necessary to overcome interactions or more extreme deficiencies. Mineral nutrition and balance is key to animal performance and productivity. Take some time to evaluate your mineral program and determine if your mineral supplement is meeting the cattle’s needs. It is often stated that mineral supplements are formulated for the region, but there can be huge variations in mineral content of forages from one side of your ranch to the other. It might be time to sample your forages and water to get a better understanding of what is available to your cows and what they need in the form of a custom-formulated supplement. The final article in this series will address reading the mineral tag and understanding bioavailability of the ingredients in mineral supplements. source; drovers..