Ebola, Zika now WIV1-CoV,

Researchers from the University of North Carolina (UNC) at Chapel Hill have found that the newly identified virus, known as WIV1-CoV, a SARS-like virus found in Chinese horseshoe bats may be poised to infect humans could bind to the same receptors as SARS-CoV that infected thousands in 2002.They also showed that the virus readily and efficiently replicated in cultured human airway tissues, suggesting an ability to jump directly to humans. Researcher Vineet Menachery said that the capacity of this group of viruses to jump into humans is greater than originally thought, adding that while other adaptations may be required to produce an epidemic, several viral strains circulating in bat populations have already overcome the barrier of replication in human cells and suggest reemergence as a distinct possibility. He further said that this virus may never jump to humans, but if it does, WIV1-CoV has the potential to seed a new outbreak with significant consequences for both public health and the global economy.The research team also found that antibodies developed to treat SARS were effective in both human and animal tissue samples against WIV1-CoV, providing a potent treatment option if there were an outbreak. Prevention using existing vaccines against SARS would not provide protection for this new virus due to slight differences in the viral sequence and there is a limitation to treat with antibodies.This is the same as with ZMapp, the antibody approach used for Ebola, because of production at a large enough scale to treat many people. culled from journal of Proceedings of the National Academy of Sciences.

CAMELS AND MERS VIRUS.

Camels, which are bred and raised for their milk and meat and for racing, are thought to be the initial source of human outbreaks. The virus is particularly prevalent in juvenile camels, where infection results in symptoms that are similar to a common cold. The virus is thought to pass to humans when they have contact with an infected camel's body fluids. Circulation of Mers in camels poses a serious risk to human health and many scientists are worried that the virus might mutate to become better adapted to human spread. That's why scientists are trying to develop vaccines - to stop the virus infecting humans and also to reduce the amount of virus circulating in camels. Vaccination is aimed at protection;Vaccines train our immune response to recognize a virus and to wipe it out before it can infect us or before it can do any harm.The vaccine acts in 2 forms;there are two arms to this protection - antibodies and killer cells. Antibodies are proteins found in human blood and in body fluids like mucus and saliva and these attach to the virus and stop it infecting. The Killer cells, , track down virus infected cells and kill the cell before new virus is released. Some vaccines raise antibodies, some produce killer cells and some raise both. The MERS infection of humans was first described in Saudi Arabia in 2012 and Since then there have been more than 1,600 reported cases. One third of reported infections have resulted in death. Individuals with other illnesses - such as diabetes, long term lung disease or kidney failure - are particularly prone to developing life-threatening symptoms. Virus spread is limited to people who have close contact with those who are infected, such as family members and healthcare workers. There are no treatments for Mers but scientists are trying to develop an effective vaccine.

Link between eggshell colour and disease resistance.

Selection for a recently discovered immune characteristic is a potential strategy to improve general disease resistance in laying hens and thus to breed for a more robust chicken, conclude researchers of Wageningen University in PLOS ONE and Poultry Science. In addition, selection for this immune characteristic has minimal negative consequences on production, but surprisingly might have an effect on eggshell colour. The current housings systems in the poultry industry increase the spread of diseases by housing large flocks of chickens on sand. These circumstances require a robust laying hen. In 2012, housing of chicken in individual cages was banned in the EU, because of welfare issues. Nowadays, chickens are group housed on sand with space to move around freely. New challenges to keeping poultry;However, this new system also brings new challenges to keeping poultry: in this new system chickens get more easily infected through sick flock mates, or through the dirtier environment. Preventing or treating these infections is becoming more difficult, due to stringent legislations and limitations set on the use of antibiotics.There is an increased need for a robust laying hen: a chicken that maintains egg production and health, under varying and challenging environments. Breeding for improved general disease resistance could be that strategy to get this robust chicken. Breeding for disease resistance;To investigate the potential of selection for increased general disease resistance, the researchers measured NAb levels of almost 3,700 purebred ISA laying chickens. They measured total NAb levels, and NAb levels for different forms of antibodies. Heritabilities were estimated to be 0.12 for total NAb levels, and between 0.07 and 0.14 for the different NAb forms.In addition, relations between the different forms of antibodies were very high. Tom Berghof, involved in the studies, explains: "This show that there is genetic potential for selection on NAb levels. Also, it is possible to select for different forms of NAb simultaneously, because they seem to be mainly regulated by the same genes." Effect on production;Relations between immune characteristics and production characteristics have been described before in several species, and are often negative. This is in line with the resource allocation theory, which states that energy spend on immunity cannot be spend on, for example, growth. Relations between NAb and production characteristics of almost 2,400 hens were studied.Most production characteristics were found not to be regulated by the same genes as NAb. However, a small negative relation was found between egg production efficiency and one NAb form. Berghof and colleagues conclude that selection for NAb might have some negative effects on production, but these negative effects seem to be small. Eggshell colour;Remarkably, one form of NAb was found to be associated to the mother's eggshell colour and egg breaking strength. Additional analyses were done in order to get more insight in the origin of these maternal effects. Berghof states: "If eggs had a whiter eggshell, than NAb levels in the offspring were higher. If eggs had a stronger eggshell, than NAb levels in the offspring were lower. So it seems that there is some kind of relation between the eggshell and the immune system, especially for the eggshell colour." At this moment the researchers are investigating this relation, since this was never described in chickens before. Read more ; World poultry. http://www.worldpoultry.net/Broilers/Health/2015/12/Link-between-eggshell-colour-and-disease-resistance-2727330W/

VACCINATION SCHEDULE FOR HORSES.

http://www.thehorse.com/articles/35029/infographic-vaccinating-your-horse?utm_source=Newsletter&utm_medium=health-news&utm_campaign=12-16-2014