Monday, December 11, 2017

When nature gives you Zika virus ... cure cancer with it!.

When nature gives you Zika virus ... cure cancer with it!New research shows that Zika kills the kind of brain cancer cells that are hardest to treat.Each year, glioblastoma is diagnosed in about 12,000 people in the United States (including Senator John McCain). After surgery, chemotherapy and radiation treatment, a small population of glioblastoma stem cells often survives and soon begins producing new tumor cells. Because of their neurological origins and ability to create new cells, glioblastoma stem cells reminded the researchers of neuroprogenitor cells. Zika virus is known to specifically target and kill neuroprogenitor cells. The researchers tested whether the Zika virus could kill stem cells in glioblastomas removed from human patients. The virus spread through the tumors, infecting and killing the cancer stem cells while avoiding other tumor cells. This suggests that Zika infection and chemotherapy-radiation treatment could be used as complementary treatments, with one killing the bulk of the tumor cells and Zika attacking the stem cells.

New type of diabetes caused by a genetic mutation.

New type of diabetes caused by a genetic mutation.Scientific research has led to the identification of a new type of diabetes caused by a mutation in the gene RFX6. Scientists from the ULB Center for Diabetes Research and the Erasmus Hospital of the ULB, together with colleagues at the University of Exeter (UK), University of Helsinki (Finland) and Kyoto University (Japan), have identified a new type of diabetes caused by a mutation in the gene RFX6. Individuals carrying the RFX6 mutation have a high probability of developing diabetes: it can start early, before the age of 20 years, and by the age of 50 years 80% has developed the disease. It is transmitted from parents to children and may affect many generations in the same family. RFX6 diabetes often requires insulin treatment because patients have reduced insulin secretion by the pancreas.

Psoriasis severity linked to increased risk of type 2 diabetes.

Psoriasis severity linked to increased risk of type 2 diabetes. People with psoriasis are at a higher risk to develop type 2 diabetes than those without psoriasis, and the risk increases dramatically based on the severity of the disease. Researchers found people with psoriasis that covers 10 percent of their body or more are 64 percent more likely to develop diabetes than those without psoriasis, independent of traditional risk factors such as body weight. Researchers from the Perelman School of Medicine at the University of Pennsylvania found people with psoriasis that covers 10 percent of their body or more are 64 percent more likely to develop diabetes than those without psoriasis, independent of traditional risk factors such as body weight. Applying the study's findings to the number of people who have psoriasis worldwide would equate to 125,650 new cases of diabetes attributable to psoriasis per year.

Research links psoriasis, depression.

A study has shown the link between psoriasis and depression.Psoriasis is an immune-mediated disease which affects the skin and joints. It commonly causes red scaly patches to appear on the skin. The scaly patches caused by psoriasis are often called psoriasis plaques or lesions. Psoriasis plaques are areas of excessive skin cell production and inflammation. Skin rapidly accumulates at these sites and sometimes takes a silvery-white appearance. Plaques frequently occur on the skin of the elbows and knees, but can affect any area including the scalp and genitals. Psoriasis is not contagious; it cannot be passed from person to person.Using data from the National Health and Nutrition Examination Survey, Dr. Ho and his colleagues studied cases of psoriasis and depression in a pool of 12,382 adult patients. About 16.5 percent of the psoriasis patients studied met the criteria for major depression, and the odds of having major depression were doubled among psoriasis patients. The association between the two conditions remained significant even when researchers adjusted for other risk factors, including age, gender, race, body mass index, physical activity, history of alcohol use and smoking, and history of other conditions like myocardial infarction, stroke and diabetes mellitus. Dr. Ho believes the connection between psoriasis and depression may be linked to the public's stigmatization of psoriasis. The condition is highly visible on the skin, especially in the summer months when more skin is exposed, he says, and those who are unfamiliar with the disease may react unfavorably to people who have it.

How to prevent psoriasis with vanilla extract.

How to prevent psoriasis with vanilla extract. Psoriasis is an inflammatory skin disorder that affects about 125 million people worldwide, resulting in scaly red plaques that typically show up on the elbows, knees or scalp. Immune system proteins called interleukins (IL) 17 and 23 are known to be key players in the development of the condition. In a recent mouse study reported in ACS' Journal of Agricultural and Food Chemistry, researchers report that vanillin an extract of vanillia could also prevent or reduce psoriatic skin inflammation. Small amounts of artificial vanilla extract, also known as vanillin, are in a wide range of products, from baked goods to perfumes. Interestingly, vanillin can have effects on different interleukins that are involved in other inflammatory conditions and diseases.

Sunday, December 10, 2017

Diphtheria: What Exactly Is It ... And Why Is It Back?.

Diphtheria: What Exactly Is It ... And Why Is It Back? The World Health Organization says it is sending a shipment of antitoxins to Bangladesh this weekend, after six deaths in a Rohingya refugee settlement. The organization did the same last week for Yemen, where at least 30 have died of the bacterial infection, many of them children. "It is shocking that in 2017, there are children dying of an ancient disease that is vaccine-preventable and can be easily treated," says Dr. Nevio Zagaria, the WHO representative in Yemen. The bacterium that causes diphtheria can live in some people without causing them to show symptoms, which can occasionally lead to a Typhoid Mary-type situation where a person spreads it around without even realizing he has it. It spreads between people in infected coughs and sneezes. Kids can also pick it up from playing with contaminated toys. Symptoms include sore throat, a low fever and lack of appetite, followed by a visible grayish coating in the nose or throat, and a swollen throat sometimes called a "bullneck." The bacteria attach to the lining of the respiratory system and produce a poison that starts killing healthy tissue. It does so by preventing cells from creating proteins, which essentially shuts them down. After a few days, it can kill so many cells that dead tissue forms a grayish layer in the nose and throat that can make it hard to breathe or swallow. Essentially, it can choke a person on his own dead cells. If the poison also gets into the bloodstream, it can damage vital organs like the heart and kidneys. Interestingly, there are actually two layers of infection going on here, because it's a virus inside the bacterium that causes it to create the toxin in the first place. Eventually, the illness can cause nerve damage, paralysis and respiratory failure.

Pet Store Puppies Linked To Campylobacter Outbreak In People.

Pet Store Puppies Linked To Campylobacter Outbreak In People.The Centers for Disease Control and Prevention is investigating a Campylobacter outbreak in people and its link to puppies purchased from a chain of pet stores. According to the CDC, at least 39 people across seven states have confirmed or suspected cases of Campylobacter bacteria, which can cause diarrhea, abdominal pain and fever. While the investigation is ongoing, federal officials have linked it to contact with puppies sold by Petland, a chain of pet stores based in Ohio. Twelve of the confirmed cases are in Petland employees, and 27 other people who fell ill either visited a Petland, recently purchased a puppy there, or visited or live in a home with a Petland puppy. According to the CDC's announcement, nine people have been hospitalized and there are no reported deaths. Campylobacter can infect dogs, cats and humans, but most commonly the bacteria are spread through eating raw or undercooked meat. About 47 percent of raw chicken samples tested in 2011 were positive for Campylobacter, according to the CDC. Humans don't typically spread the bacteria to each other, but it is possible to be exposed through dog feces. In a typical case, symptoms last for about a week.The CDC estimates that annually, Campylobacter affects 1.3 million people. The good news is that most people get well on their own. The CDC says people typically need antibiotics only if they're immune compromised or at high risk of complications. To minimize risk of illness, the CDC suggests washing your hands after touching your dog, though for any dog lover, washing your hands every time .The CDC also recommends quickly disposing of dog poop using disposable gloves, as well as regular visits to the veterinarian to keep your dog healthy.

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