A new alternative to antibiotics.

The method of use of antibiotics in man, animals and in agriculture has been fingered as the major cause of antibiotics resistance which has emerged as a global problem. There has been various methods of curbing antibiotics use in different circles but now a latest alternative to antibiotics has been tried with successful outcomes.

 The new research carried out in Technion-Israel Institute of Technology and published recently in Nature Scientific Reports combines the use of metals and organic acids as a viable alternative to antibiotics. There has been various researches where different interventions have been applied with success. 

These numerous alternatives to antibiotics are already being tested by different researchers around the world. Two of the most popular alternatives are the use of metals such as silver, zinc, and copper which were used in ancient Egypt and Greece for treating infection and purifying water sources, and the use of organic acids such as food acid that is used as a preservative in the food industry.

 This new research now combined the 2 alternatives which is organic acids and metals at a low concentration, and found that the combination is extremely effective in eradicating pathogenic bacteria such as cholera, salmonella, and Pseudomonas, as well as eliminating bacteria that attack agricultural crops such as tomatoes, melons, and apples.

Healthy tips for raising antibiotic free broilers (ABF).

An Indiana-based producer with more than 15 years’ experience raising broilers without antibiotics — offers these tips for ensuring a strong, healthy and efficient bird: Muller poultry has been raising broilers without antibiotics (ABF) and these are their tips. 

 1) Start with healthy stock that have been proven over the years.Miller Poultry now exclusively raises Aviagen Ross 708. While the line has a reputation for being a “big-bird breed” that requires more nutrients than other lines, they seem to have fewer leg problems — a common trouble spot in ABF production — and a higher yield at processing, according to live operations director Stephen Shepard. 

 2) Understand that gut health is the key to success in production. Birds with healthy guts absorbs food properly,grow fast and are disease free. Coccidiosis and necrotic enteritis (NE) are their biggest health challenges. To help prevent coccidiosis — a prerequisite for managing NE — Miller Poultry leans on vaccines all year long for its organic birds.

 3) lightening techniques,the first 7 days in the life of birds are critical and hence great care must be taken to ensure growth and stability. The lightening procedure of lights on to ensure birds can see at night for feed can be manipulated for better effects. 

The use of LED lights have been shown to boost growth and hence productivity. see Miller Poultry is experimenting with LED tube lights along the water and feed lines, making the inside of a dimly lighted broiler house look like an airport runway at night. 

The lighting, Shepard says, attracts the birds and ensures good feed and water intake. 4) Rotate medication ,feed and vaccines. Miller Poultry was a big user of a recombinant vaccine for Marek’s disease and infectious bursal disease (IBD). In recent years, however, they’ve been rotating in traditional live IBD vaccines to get better protection against shedding — a known shortcoming with continuous use of recombinants. 

 Maintaining healthy bursas is important in any production system, it is especially critical for ABF operations to help optimize immunity. 

 5) Vaccinating year-round for Escherichia coli is a common practice in the industry for broiler-breeders and layers.E. coli typically emerges in broilers as a secondary infection to infectious bronchitis virus or reovirus, and can lead to high numbers of condemnations in the processing plant when birds are harvested . 

 Miller poultry administers the E. coli vaccine at day 1 via hatchery spray, sometimes in combination with a coccidiosis vaccine.

How bacteria develop antibiotic resistance.

A study from the Hebrew University of Jerusalem has shown how bacteria evolve and resist antibiotics. The scientists Using quantitative approaches from physics, biophysicists discovered a surprising way that bacteria can evolve resistance to antibiotics. 

 The new research published in the journal Science, researchers at the Hebrew University of Jerusalem report a startling alternative path to the evolution of resistance in bacteria.The bacteria evolve a sleeping mechanism after which the bacteria can then wake up and evolve resistance 20 times faster than normal -- at which point continuing to administer antibiotics won't kill the bacteria. 

 The results indicate that tolerance may play a crucial role in the evolution of resistance in bacterial populations under cyclic exposures to high antibiotic concentrations. To investigate this evolutionary process a group of biophysicists,exposed bacterial populations to a daily dose of antibiotics in controlled laboratory conditions, until resistance was established. 

By tracking the bacteria along the evolutionary process, they found that the lethal antibiotic dosage gave rise to bacteria that were transiently dormant, and were therefore protected from several types of antibiotics that target actively growing bacteria. 

 Once bacteria acquired the ability to go dormant, which is termed tolerance, they rapidly acquired mutations to resistance and were able to overcome the antibiotic treatment. First the bacteria evolved to sleep for most of the antibiotic treatment, and then this "sleeping mode" not only transiently protected them from the lethal action of the drug, but also actually worked as a stepping stone for the later acquisition of resistance factors.

Food Safety : Use of banned drugs in food animal production and the health implication in man.

Animals raised and processed for food have a great deal of impact on the health and well being of man. The saying "you are what you eat" hold true ,as whatever you throw in or gulp down shows up in terms of fat or a trim frame. 

Now a days the term is modified to you are "what your animals eat", meaning if you feed crap,you get crap at the end. The business of raising animals for consumption is not a minor issue, aside the monetary issue(profit margin),the health status of the animals and by extension humans that consume these products is very important as the drugs used in the production line must be safe for the animals and humans as well. 

 The superbugs issue has actually been traced to misuse or overuse of antibiotics in food animal production and this has birthed the antibiotic free production movement ,everyone is alert and aware of nutrients,health benefits,side effects and most importantly,people are going organic. 

This awareness has helped to enforce certain regulation and formulation of new regulations regarding what drugs to use and what not to administer during production. The regulation coupled with surveillance and strict inspection during slaughter to test for residues has helped to prevent greedy producers from passing dangerous products to the public. 

 This is the case of a cattle breeder;Stanley Richardson (67) from Woodford, Newtowngore,convicted and fined €500 and ordered to pay costs of €5,000 after he was found guilty of selling an animal which had been given bute, a banned substance.

Richardson was found guilty of selling a bull which had been administered the banned substance phenylbutazone, also known as bute. 

 Phenylbutazone is known to induce blood dyscrasias, including aplastic anemia, leukopenia, agranulocytosis, and thrombocytopenia, and can result in death. Hypersensitivity reactions of the serum-sickness type have also been reported. 

 The banned substance has the potential to have a carcinogenic effect on humans, thus why it is prohibited in food producing animals. Bute can be used to treat horses, as it is a non-steroidal anti-inflammatory drug, provided horses treated are not intended for human consumption.