FOODS DANGEROUS TO PETS.

CAPSULE ENDOSCOPY AS A DIAGNOSTIC TOOL IN HORSES.

A new technique has been developed to ease diagnosis issues in horses,the procedure uses a camera pill to aid visualization of the gut. The research was carried out by veterinary researcher Dr. Julia Montgomery in the U of S Western College of Veterinary Medicine. Montgomery worked with equine surgeon Dr. Joe Bracamonte and Khan Wahid, a specialist in health informatics and imaging in the College of Engineering. The team used an endoscopy capsule about the size and shape of a vitamin pill with a camera to have a look inside a horse. The capsule pill endoscopy offers a powerful new tool to diagnose diseases such as inflammatory bowel disease and cancer, or to check surgical sites. Researchers could use it to see how well drugs to stimulate bowel action are working, or to answer basic questions such as determining what normal small intestine function looks like. The advantage of this method of diagnosis is that the inside of the horse can be viewed and a better understanding gained as to the normal operations of the intestine,with little or no stress to the animal. The other forms of diagnosis prior to this are endoscopy,exploratory surgery, or laparascopy. The "camera pills" have been in use for human medicine for some time, but have just been used in equine health. The team used in the horse by administering the capsule through a stomach tube directly to the horse's stomach. The journey down the track was noted for the next eight hours, as the capsule and its camera made its way through the horse's small intestine, offering a continuous picture of what was going on. This will really ease diagnosis issues and speed up treatment in horses,thus ensuring equine health is maintained when eventually available.The team plans to run more tests in the next few months on different horses to gather more data so as to provide capsule pill specific to the horses. diagnosis# diagnostic kits# equine health # data #

Poultry vaccines nullify antibiotic need

Poultry vaccines nullify antibiotic need: The Ceva Poultry Vaccinology Summit in Barcelona has said vaccines, not antibiotics, are the long-term solution to the prevention of dangerous poultry diseases like avian influenza (AI).

Ukraine hit with African swine fever

Ukraine hit with African swine fever: A farm in the Kirovograd region of Ukraine has had to slaughter more than a dozen pigs after the African swine fever (ASF) disease was detected by health officials this week.

Alzheimer's could be treated with lab grown neural networks.

A team from Rutgers University, in a study published in Nature Communications, states that neuro-degenerative diseases like Alzheimer's, Parkinson's could be treated with the help of a new, lab-grown, neural network. This is done by injecting neural networks into damaged mice brains a process that could help with treatment of such diseases.The process, which researchers refer to as "3D micro-scaffolding", has several stages. Neurons are grown in a lab by exposing stem cells to proteins, meaning they develop into neurons. These neurons grow inside the 'scaffold' of polymer fibres and are subsequently injected, as a network, into the brain. Several neurons, and neural networks, were injected into diseased mice brains. The researchers found that networks, rather than individual neurons, were far better at surviving in the brain - 40 percent more likely to survive, in some cases.This is a promising new platform that could make the transplantation of neurons a viable treatment for a broad range of human neuro-degenerative disorders . Though the team is as yet unsure how the neural networks will prevent the progression of the disease, they are hopeful that it will help treat the damage caused by degenerative diseases. culled from wired.co.uk

BIOTEMPUS AND CANCER TREATMENT IN DOGS.

Melbourne based biotechnology company Biotempus has made a remarkable discovery: cancer patients’ [both canine and human] immune systems run on a cycle and thus delivering treatment at the wrong times could be reducing the efficacy. Dr Noam Pik, the general manager at ASAP Laboratory, explained they hypothesised that a seven-day cycle was the key to the efficacy of treatment by building on previous medical research. “This discovery was made by Martin Ashdown while investigating AIDS with mice after noticing some responded better to the same treatment at different times post inoculation,” said Dr Pik. “This lead to the hypothesis that the immune system operates differently in the time domain. That is, at certain times it is more effective at eliminating disease.” Read more here; vetpracticemag.com.au/on-the-cusp-of-a-breakthrough/

CANINE CANCER TRIALS AND CANCER TREATMENT IN MAN.

MELBOURNE scientists say a new canine cancer trial has produced exciting results that could lead to a breakthrough in human treatment.Dr Noam Pik, head of the veterinary division at West Melbourne biotechnology research group Biotempus, is leading the free clinical trial and said early results were mind-blowing The 12-month trial, which is being conducted at 20 veterinary clinics around Australia, was launched in December and according to Dr Pik, several dogs had already shown signs of remission. Dr Pik said dogs were given a single dose of chemotherapy — a tablet — that did not target the tumour, but attacked (T-Regulatory) cells within the patient’s own immune system.If this trial proves effective, they plan to offer this service to canine patients within 24 months and then continue to humans. These cells suppressed the natural cancer-fighting mechanism of other (T-Effector) cells in the immune system ,if the T-Regulatory cells can be selectively killed, the T-Effector cells can get on with the job of eliminating cancer undisturbed. This method has been researched before but Dr Pik’s team has discovered a way to predict when the suppressor cells are most vulnerable — the optimum time to administer the chemo and kill the cells. The team discovered the immune system moves in cycles and can be mapped. Dogs are required to give blood samples every second day for up to three weeks, so experts can track their immune cycle and identify the best time to administer the drug. The last decade of research has shown considerable progress in the field of immunotherapy — using the patients’ own immune system to fight the cancer. The contribution of the tumor micro-environment is immense and has been previously largely underestimated. Thus, we believe it is important to aim treatment at both the tumor itself and the tumor environment with the aim of achieving more effective and durable cancer treatments. The chemo tablets cost less than $5, the treatment could potentially slash the cost of canine cancer treatment. The low-dose tablet is strong enough to correct the immune imbalance without the harsh side effects usually associated with chemo, such as nausea.