The research was led by the RIKEN Centre for Developmental Biology in collaboration with Tokyo University of Science, been published in Science Advance. A Japanese lab has grown a 3D layer of skin that can sweat and sprout hairs. The skin has sweat glands, follicles, sebaceous glands and three layers of skin cells. The researchers behind the study said the skin was able to "connect to other organ systems such as nerves and muscle fibres" and could eventually be used to treat burns patients or those requiring "new skin".
The team used cells from the gums of mice to create stem cells, which were then then developed into an "embryoid body". The researchers described this as "a three-dimensional clump of cells that partially resembles the developing embryo in an actual body".
The cells were then implanted into bald mice, where they connected with nerve and muscle tissues and "functioned normally", according to the team. Up until now, artificial skin development has been hampered by the fact that the skin lacked the important organs, such as hair follicles and exocrine glands, which allow the skin to play its important role in regulation.
This new technique has successfully grown skin that replicates the function of normal tissue, bringing us closer to the dream of being able to recreate actual organs in the lab for transplantation, and also believe that tissue grown through this method could be used as an alternative to animal testing of chemicals.
Source;wired.co.uk
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Showing posts with label skin grafts. Show all posts
Showing posts with label skin grafts. Show all posts
Monday, April 4, 2016
3D -GROWN SKIN SWEATS AND SPROUTS HAIR.
The research was led by the RIKEN Centre for Developmental Biology in collaboration with Tokyo University of Science, been published in Science Advance. A Japanese lab has grown a 3D layer of skin that can sweat and sprout hairs. The skin has sweat glands, follicles, sebaceous glands and three layers of skin cells. The researchers behind the study said the skin was able to "connect to other organ systems such as nerves and muscle fibres" and could eventually be used to treat burns patients or those requiring "new skin".
The team used cells from the gums of mice to create stem cells, which were then then developed into an "embryoid body". The researchers described this as "a three-dimensional clump of cells that partially resembles the developing embryo in an actual body".
The cells were then implanted into bald mice, where they connected with nerve and muscle tissues and "functioned normally", according to the team. Up until now, artificial skin development has been hampered by the fact that the skin lacked the important organs, such as hair follicles and exocrine glands, which allow the skin to play its important role in regulation.
This new technique has successfully grown skin that replicates the function of normal tissue, bringing us closer to the dream of being able to recreate actual organs in the lab for transplantation, and also believe that tissue grown through this method could be used as an alternative to animal testing of chemicals.
Source;wired.co.uk
Saturday, November 28, 2015
WOUND RECONSTRUCTION IN HORSES.
These grafts involve relocating the skin from a donor site to cover a wound and restore function and cosmetics in your veterinary equine patients.In horses, skin grafts are most often used for limb wounds where primary closure is not possible or second intention healing is delayed or not occurring. Grafts may also be considered for large wounds of the trunk, as grafting will decrease healing time. This article concentrates on free skin grafts, with an emphasis on punch grafts. With free skin grafts, the donor skin is severed from its blood supply and relocated to a wound.
Free skin grafts are categorized by thickness and type. Full-thickness grafts include epidermis and the entire dermis. Split-thickness grafts include epidermis and a portion of dermis. Full- and split-thickness grafts can be either sheet grafts or island grafts. Sheet grafts are applied to the surface of a wound, and island grafts are embedded in the wound (Figure 1). Island graft techniques include punch, pinch, tunnel and modified meek grafts. The advantage of island grafts is that the failure or loss of one graft does not affect other grafts in the wound.
read more here;http://veterinarynews.dvm360.com/wound-reconstruction-free-skin-grafts-horses
read more here;http://veterinarynews.dvm360.com/wound-reconstruction-free-skin-grafts-horses
WOUND RECONSTRUCTION IN HORSES.
These grafts involve relocating the skin from a donor site to cover a wound and restore function and cosmetics in your veterinary equine patients.In horses, skin grafts are most often used for limb wounds where primary closure is not possible or second intention healing is delayed or not occurring. Grafts may also be considered for large wounds of the trunk, as grafting will decrease healing time. This article concentrates on free skin grafts, with an emphasis on punch grafts. With free skin grafts, the donor skin is severed from its blood supply and relocated to a wound.
Free skin grafts are categorized by thickness and type. Full-thickness grafts include epidermis and the entire dermis. Split-thickness grafts include epidermis and a portion of dermis. Full- and split-thickness grafts can be either sheet grafts or island grafts. Sheet grafts are applied to the surface of a wound, and island grafts are embedded in the wound (Figure 1). Island graft techniques include punch, pinch, tunnel and modified meek grafts. The advantage of island grafts is that the failure or loss of one graft does not affect other grafts in the wound.
read more here;http://veterinarynews.dvm360.com/wound-reconstruction-free-skin-grafts-horses
read more here;http://veterinarynews.dvm360.com/wound-reconstruction-free-skin-grafts-horses
WOUND RECONSTRUCTION IN HORSES.
These grafts involve relocating the skin from a donor site to cover a wound and restore function and cosmetics in your veterinary equine patients.In horses, skin grafts are most often used for limb wounds where primary closure is not possible or second intention healing is delayed or not occurring. Grafts may also be considered for large wounds of the trunk, as grafting will decrease healing time. This article concentrates on free skin grafts, with an emphasis on punch grafts. With free skin grafts, the donor skin is severed from its blood supply and relocated to a wound.
Free skin grafts are categorized by thickness and type. Full-thickness grafts include epidermis and the entire dermis. Split-thickness grafts include epidermis and a portion of dermis. Full- and split-thickness grafts can be either sheet grafts or island grafts. Sheet grafts are applied to the surface of a wound, and island grafts are embedded in the wound (Figure 1). Island graft techniques include punch, pinch, tunnel and modified meek grafts. The advantage of island grafts is that the failure or loss of one graft does not affect other grafts in the wound.
read more here;http://veterinarynews.dvm360.com/wound-reconstruction-free-skin-grafts-horses
read more here;http://veterinarynews.dvm360.com/wound-reconstruction-free-skin-grafts-horses
WOUND RECONSTRUCTION IN HORSES.
These grafts involve relocating the skin from a donor site to cover a wound and restore function and cosmetics in your veterinary equine patients.In horses, skin grafts are most often used for limb wounds where primary closure is not possible or second intention healing is delayed or not occurring. Grafts may also be considered for large wounds of the trunk, as grafting will decrease healing time. This article concentrates on free skin grafts, with an emphasis on punch grafts. With free skin grafts, the donor skin is severed from its blood supply and relocated to a wound.
Free skin grafts are categorized by thickness and type. Full-thickness grafts include epidermis and the entire dermis. Split-thickness grafts include epidermis and a portion of dermis. Full- and split-thickness grafts can be either sheet grafts or island grafts. Sheet grafts are applied to the surface of a wound, and island grafts are embedded in the wound (Figure 1). Island graft techniques include punch, pinch, tunnel and modified meek grafts. The advantage of island grafts is that the failure or loss of one graft does not affect other grafts in the wound.
read more here;http://veterinarynews.dvm360.com/wound-reconstruction-free-skin-grafts-horses
read more here;http://veterinarynews.dvm360.com/wound-reconstruction-free-skin-grafts-horses
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