First confirmed human infection of zoonotic parasite reported in Vietnam.

Researchers have reported the first laboratory-confirmed case of Trypanosoma evansi infection in a Vietnamese woman with no deficiencies. They linked transmission of the parasite with bovid exposure. Over half of Vietnam’s population resides in rural areas, and most participate in small-scale animal production, which likely facilitates the transfer of pathogens from animals into humans,” the researchers wrote. “T. evansi is associated with acute disease in camels and horses and chronic disease in cattle and buffalo, and can be found in South America, North Africa, the Middle East, South and Southeast Asia.” There have been four probable cases of T. evansi infection reported worldwide that lacked molecular parasite speciation. One previous case was reported in India in 2005 with molecular confirmation, although the patient had a deficiency of Apolipoprotein L1 (APOL1), a serum component with trypanocidal activity. The present case, a previously healthy Vietnamese woman aged 38 years with no APOL1 deficiency, first presented to a health care facility with 18 days of fever, headache and arthralgia. She had no history of travel to any regions where T. evansi has been observed. Although initially treated for malaria, microscopic examination of blood samples revealed unicellular flagellate protozoa with the morphology of Trypanosoma. The patient received a treatment reported to have trypanocidal activity for 7 days, but returned with symptoms 6 weeks after discharge and subsequently treated with a first-line anti-trypanosomal treatment and eventually recovered with no complications. PCR amplification and serological testing of the patient’s serum confirmed the infecting species as T. evansi, and APOL1 testing found the patient’s concentrations to be within a healthy range. As the patient reported potential exposure while butchering locally reared beef, the researchers conducted a census of livestock farms surrounding the patient’s relatives’ household. Blood samples from some cattle and buffalo were indicative of T. evansi infection, and some farmers reported a mystery illness affecting their livestock. These data helped the researchers conclude that these bovid were the likely source of the patient’s infection. Furthermore, the parasite may have been circulating among Vietnamese livestock for some time while avoiding detection, and if endemic could have further economic and human health consequences for the region. “Subsequent field investigations demonstrated a high prevalence of bovids in the immediate environs of the patient with clinical and molecular evidence of T. evansi infection,” the researchers wrote. “Further research is required to better understand this zoonotic pathogen, including host susceptibility factors, potential vectors and therapeutic options for both human and animal infections.” – story source; Helio infectious news.oo

BRAZIL CONFIRMS ZIKA INFECTION THROUGH BLOOD TRANSFUSION.

Brazilian health authorities confirmed on Thursday a case of transmission of Zika through a transfusion of blood from a donor who had been infected with the mosquito-borne virus that is spreading rapidly through the Americas.The health department of Campinas, an industrial city near Sao Paulo, said a man with gunshot wounds became infected with Zika after multiple blood transfusions in April 2015. Officials said they determined that one of the people whose donated blood was used in the transfusion had been infected with Zika. Zika is usually contracted via mosquito bites, so transmission of the illness through blood transfusions adds another concern to efforts to contain the outbreak. Some countries have tightened procedures for blood donations, to protect blood supplies. Zika has been reported in 30 countries since it first appeared in the Americas last year in Brazil, where it has been linked to thousands of babies being born with microcephaly. This is a condition where infants have abnormally small heads and often have underdeveloped brains. Campinas health officials said the donor of the contaminated blood developed symptoms afterwards that were mistaken for dengue, a virus borne by the same mosquito that transmits Zika. A blood test that showed he had Zika was not completed until Jan. 28 this year. The blood center at the University of Campinas said a second person who donated blood in May developed symptoms and tested positive for Zika, though the recipient of the contaminated blood has not developed symptoms of the virus. Brazil’s Health Ministry said the first recipient died of his wounds and not from the Zika infection. It said it was reinforcing instructions to blood banks that people infected with Zika or dengue not be permitted to donate blood for 30 days after full recovery from the active stage of Zika infection. The American Red Cross urged prospective donors who have visited Zika outbreak zones to wait at least 28 days before giving blood, but said the risk of transmitting the virus through blood donations was “extremely” low in the continental United States. The agency asked donors who give blood and subsequently develop symptoms consistent with Zika within 14 days to notify the Red Cross so the product can be quarantined. Also causing concern is the possibility of transmission through sexual contact. Health officials in Texas reported on Tuesday that a person in Dallas became infected after having sex with another person who had traveled in Venezuela, where the virus is circulating. story source;news daily.(http://newsdaily.com/2016/02/brazil-confirms-zika-infection-from-a-blood-transfusion/)

FACTS ABOUT ZIKA VIRUS.

An RNA virus of flaviviridae family and genus flavi virus.Transmission is through the bite of an infected Aedes aegypti mosquito.The mosquitoes are urban dwellers and aggressive day time feeders,feeding both in door and outdoor.The zika virus infection is an emerging mosquito borne illness,1st identified in Uganda in 1947. 1 in every 5 people infected with the zika virus become ill,and the common symptoms of zika are 1) fever 2)rash 3)joint pain 4)red eyes,while other signs include muscle pain and headache.The illness is usually mild with symptoms lasting for several days to weeks. Pregnant women infected with the virus have babies with small brains,resulting in delayed development. The symptoms of the zika virus are similar to that of dengue and chikungunya. The zika virus remains in the blood of an infected person for 2-7 days but can be longer in some people. There are no vaccines or medication to prevent the zika virus infection,rather symptoms are treated symptomatically following these steps 1) get plenty of rest. 2) drink plenty of fluid to prevent dehydration and 3) use acetaminophen to relieve fever and pain. An infected mosquito can spread virus to other people.People living in areas with high mosquito population should protect themselves by using screened doors,windows ,insecticides and insect repellent. # stay safe # insecticides # treated nets

"African Swine Fever is a man-made disease"

Dr Klaus Depner and Dr Sandra Blome, of the Friedrich-Loeffler-Institut in Germany have new insights about the virus , they have studied cases and are of the opinion that “Most problems are a matter of human misbehavior.”

 African Swine Fever, it should be that the major threat with regard to the virus is not the virus itself, but how humans deal with it.Trials at the FLI showed that there is no difference in the way the ASF virus affects wild boars or domestic pigs.

Logically, one of the major questions that the researchers had when ASF was introduced in 2007 in the Caucasus was: how would the virus spread and behave in wild boars? Depner: “Essentially, we had two hypotheses.

The first one was that the disease in wild boars would die out due to the high virulence of the virus.”Blome: “Roughly, the animals get sick four days after infection.”Depner: “Usually death will follow within three to six days, .

This means that almost all infected hosts will die very quickly, which means that the virus will cease to exist very soon because it kills its host.

In that case, we would not have to worry, ASF would do its job extinguishing itself.”Blome, however, points to the fact that ASF virus is not that contagious. High viral loads are found in blood, but saliva or faeces contain less virus:

“We overestimated the contagiousness of African Swine Fever. The disease moves very slowly. When looking at affected wild boar populations, most of them have not been significantly reduced. The virus doesn’t spread that quickly at all.” Blome adds, “Wild boars shed the virus mainly when they are very sick and in the final stage of the disease.

When the animals have high fever it’s in their character to stay where they are, and they are certainly not going to walk very far when they feel bad.”Depner: “So what we have here is a virus that is very stable in its environment without fast movement. It neither dies out, nor moves.

 Undisposed carcasses of infected wild boars remain infectious for a long time in the environment and become a source of infection for healthy animals.” The human factor; its usually a case of human misbehavior. What happened is that infected meat made it to the market.

When many pigs started to die, they were sent to slaughter. Pig prices dropped, cheap meat entered the market and the meat made its way into homes – and into suitcases. This is how the virus dispersed.

 The virus spread along the main roads, the transport routes. This spread bears a 100% human mark.” Humans can be identified as having aggravated the situation ever since as well.

 Since wild boars have often been thought to be spreading the virus, in several countries attempts were launched to eradicate them – Poor bio security protocols have also been identified as cause of spread of the virus.

Bio security measures include the following; Changing clothes, working hygienically and making sure nothing from the outside reaches the inside.

 Story credit; world poultry.

HENDRA VIRUS, HORSES AND HORSE OWNERS.

The Hendra virus is a virus that mainly infects fruit bats also called flying foxes which can be passed on to horses, people and other animals. The virus is a deadly zoonoses. Hendra virus is very fragile. It is easily killed by heat, soap or detergents and by desiccation (drying out). It may survive in the environment from several hours to several days depending on environmental conditions. Survival is longer in cool moist conditions where the pH is close to neutral. Horses can shed Hendra virus before they show any sign of illness. All horse handlers should protect themselves by routinely using good hygiene practices whenever handling horses.Always cover any cuts exposed skin before handling your horse. Always wash your hands with soap and water, particularly after handling your horse's mouth or nose. Do not smoke, eat or touch your eyes, nose or mouth until you have washed your hands, every time you put a bridle on or take it off you are likely to contact the horse's saliva. The Hendra virus should be suspected whenever a horse's health deteriorates rapidly. The symptoms in horses include a sudden fever with a respiratory or neurological illness and rapid death, laboured breathing ,frothy and/or blood stained nasal discharge ,a temperature above 40 degreesC. The neurological changes are tilting of the head, loss of vision, abnormal muscle twitching, weakness and loss of balance. Some horses show colic symptoms. What to do when horses have been confirmed to have the virus; 1)quarantine. 2) protective clothing .Everyone handling a sick horse must wear full protective clothing. Protective clothing must be fitted correctly. Put on protective clothing before approaching the horse.After handling the horse, remove and dispose of protective clothing carefully into waste bags, making sure there is no contact with your face, particularly your eyes, mouth and nose.Carefully remove any clothing contaminated with the horse's body fluids. Wash your hands thoroughly after removing the protective clothing and horse owners should always have a protective clothing for safety. Vaccination of horses is very important.

FEVER IN DOGS.

Fever refers to an elevated temperature, also called hyperthermia occurs when the body temperature of the dog is way past the normal range.Fever is not a disease but an indication that pet is fighting an infection.Infections and inflammation results in fever in dogs.When a pet is exposed to infection or there is an underlying inflammatory reaction,the body's first response is to fight the infection and this is characterized with an elevated temperature. Fever occurs in bacterial,viral, fungal infection, cases of abscess,urinary tract infection and pneumonia. The cause can sometimes be unknown and its associated with immune system, fever if prolonged results in damage of internal organs. The common signs associated with fever are 1) inappetence. 2) weakness 3)depression 4) shivering 5)coughing 6) dehydration. Treatment; check older post.

FEELING BLUE!!!

Horsy conversation!!! feeling blue. A little bit under the weather? cold and chills??, fever??? Can you help???