Workers at industrial farms carry drug-resistant bacteria associated with livestock.

Workers at industrial farms carry drug-resistant bacteria associated with livestock. A new study found drug-resistant bacteria associated with livestock in the noses of industrial livestock workers in North Carolina but not in the noses of antibiotic-free livestock workers. The drug-resistant bacteria examined were Staphylococcus aureus, commonly known as "Staph," which include the well-known bug MRSA (methicillin-resistant Staphylococcus aureus).New Staph strains are emerging in people who have close contact with livestock animals and for this reason have been given the name livestock-associated Staph. While everyone in the study had direct or indirect contact with livestock, only industrial workers carried antibiotic-resistant Staph with multiple genetic characteristics linked to livestock. Many industrial livestock operations raise animals in large conferment buildings and use antibiotics, including non-therapeutically in animals' feed and water to promote their growth. Previous studies have detected strains of drug-resistant S. aureus from livestock, first among farm workers, and subsequently in hospital and community settings in Europe. S. aureus can cause a range of illnesses in humans, from minor to life-threatening skin, bloodstream, respiratory, urinary and surgical site infections. Like most illnesses caused by bacteria, S. aureus infections are treated with antibiotics. According to the Centers for Disease Control and Prevention, some Staph cannot be killed by antibiotics, meaning they are resistant.

Reverse zoonosis. How human pathogens affect animals.

Reverse zoonosis. The fact that diseases can pass from humans to animals is, perhaps, not such a surprise. An estimated 61.6 percent of human pathogens are regarded as multiple species pathogens and are able to infect a range of animals.

 Also, over 77 percent of pathogens that infect livestock are multiple species pathogens. One of the earliest studies demonstrating reverse zoonosis was conducted in 1988 and looked at dermatophytes - fungi that cause superficial infections of the skin, nails, and hair - including Microsporum and Trichophyton.

The authors found that these fungi could be transmitted from animal to animal, human to human, animal to human, and human to animal.

 From 2000, studies began to emerge investigating the ability of certain parasites to pass from human to animal, including Giardia duodenalis (the parasite responsible of giardiasis), and Cryptosporidium parvum (a microscopic parasite that causes the diarrheal disease cryptosporidiosis) A CASE OF .Reverse zoonosis. 

 A study, published in the journal Veterinary Microbiology in 2006, looked at methicillin-resistant Staphylococcus aureus (MRSA) in pets and its transmission between humans and animals.The paper mentions a specific case in which a couple was repeatedly infected with MRSA.

The re-infections only stopped once their dog was identified as the source and treated. It is presumed that the dog was initially infected by the couple and then passed the infection back to them each time they had been successfully treated.

 The emergence of MRSA in household pets is of concern in terms of animal health and the potential for animals to act as sources of infection or colonization of human contacts.Reverse zoonosis.

 A paper, published in 2004, describes the case of a 3-year-old Yorkshire terrier who arrived at the University of Tennessee College of Veterinary Medicine with anorexia, vomiting, and a persistent cough. After running a barrage of tests - including, sadly, an eventual postmortem - the authors concluded that it had contracted tuberculosis (TB) (Mycobacterium tuberculosis).

The dog's owner had been receiving treatment for TB for 6 months. This was the first documented transmission of TB from human to canine.

 In 2009, the first recorded case of fatal human-to-cat transmission of the H1N1 flu virus occurred in Oregon. The owner of the cat had a severe case of influenza and had to be taken to the hospital. Her cat - an indoor cat with no exposure to other people or animals - later died of pneumonia caused by an H1N1 infection.
Details of the case were published in the journal Veterinary Pathology. In 2011 and 2012, researchers identified more than 13 cats and one dog with pandemic H1N1 infection that appeared to have come from human contact. Interestingly, the animals' symptoms were similar to those experienced by human carriers - rapidly developing respiratory disease, a lack of appetite and, in some cases, death.

Drug-resistant genes spread through environment, not meat products.

New findings show that traffic from humans to animals, and back to humans via the environment,is responsible for resistant genes and as such a new focus on tackling antibiotic resistance is proposed. 

In the first study to track antibiotic resistance in intensively-farmed beef, scientists discovered a "startling" lack of resistance genes in meat. Meanwhile, in soil and feces samples from cattle pens they found genes resistant to a powerful "last resort" class of antibiotics called carpabemens that aren't used in the livestock industry.

These genes may have jumped from humans or companion animals to livestock, or could even be present at low levels in the wider environment.

 Results published in eLife suggest researchers and policy-makers need to switch focus to combat the growing problem of drug-resistant bugs. A current focus for policy-makers is to reduce antibiotic use in livestock to curb the spread of drug-resistant bugs.


The team urges that traffic from humans to animals, and back to humans via the environment, should be a new focus for research. The lack of resistance genes in post-slaughter meat samples was a big surprise for the scientists, forcing them to rethink the view that it is only antibiotic use that increases resistance.

 Environmental routes of exposure are much harder to trace and have been largely overlooked by researchers and policy-makers. While many people never step foot on working farms, we are physically connected to agriculture via waste water run-off and wind borne particulates.

 The scientists suggest investigating wind patterns and water flow to see if, and how, resistant bacteria may be disseminated, and how far.

 The researchers opined that they may observe that such dissemination is very limited geographically, or we may find that resistant bacteria can travel long distances if they find the right currents or the right waterways. In either case, this would be very important information from a public health perspective.

 The researchers collected samples from 1,741 commercial cattle. The study started in feedlots, where intensively farmed cattle are moved after grazing. A feedlot consists of outdoor pens where cattle are fattened during their final months of life.

 Samples were also taken during slaughter and from market-ready products. No previous studies have tracked antimicrobial use and resistance right through the beef production process.

The team found no resistance genes to any bacteria in market-ready beef products. They did discover changes to antibiotic resistance genes in the guts of cattle during their time in the feedlot. The changes could be due to the use of antibiotics in feedlots but could also result from adjusting to a high-energy diet or from the cattle's maturation from adolescent to adult.

ANTIBIOTIC MISUSE IN ANIMALS AND EFFECT ON MAN.

The world organisation for animal health aims to reduce misuse of antibiotics, because of growing threat of antibiotic resistance bacterial.

An awareness week has been organized in collaboration with world health organization, read details here;http://www.globalmeatnews.com/Industry-Markets/Animal-health-body-targets-misuse-of-antibiotics?utm_source=copyright&utm_medium=OnSite&utm_campaign=copyright