COVID-19: Research shows children are silent spreaders of SARS-CoV-2.

In the most comprehensive study of COVID-19 pediatric patients to date, researchers provide critical data showing that children play a larger role in the community spread of COVID-19 than previously thought.

 In a study of 192 children ages 0-22, 49 children tested positive for SARS-CoV-2, and an additional 18 children had late-onset, COVID-19-related illness.

 The infected children were shown to have a significantly higher level of virus in their airways than hospitalized adults in ICUs for COVID-19 treatment, according to Harvard-affiliated Massachusetts General Hospital (MGH) and Mass General Hospital for Children (MGHfC).

 The study, “Pediatric SARS-CoV-2: Clinical Presentation, Infectivity, and Immune Reponses,” was published in The Journal of Pediatrics.

Findings from nose and throat swabs and blood samples from the MGHfC Pediatric COVID-19 Biorepository carry implications for the reopening of schools, daycare centers and other locations with a high density of children and close interaction with teachers and staff members.

 The researchers note that although children with COVID-19 are not as likely to become as seriously ill as adults, as asymptomatic carriers or carriers with few symptoms attending school, they can spread infection and bring the virus into their homes.